34 — 6 (44) 2022 — Khaydarova F.A., Alimov A.V., Alieva A.V., Khalilova D.Z., Tojieva I.M., Talenova V.A., Alimova N.U., FEATURES OF THE CLINICAL COVID-19 DEPENDING ON THE PRESENCE OR ABSENCE OF HYPERGLYCEMIA ON THE EXAMPLE OF TASHKENT CITY IN 2020

FEATURES OF THE CLINICAL COVID-19 DEPENDING ON THE PRESENCE OR ABSENCE OF HYPERGLYCEMIA ON THE EXAMPLE OF TASHKENT CITY IN 2020

Khaydarova F.A., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Alimov A.V., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Alieva A.V., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Khalilova D.Z., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Tojieva I.M., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Talenova V.A., Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Alimova N.U.,Republican Specialized Scientific and Practical Medical Center of Endocrinology named after academician Ya.Kh.Turakulov

Resume

Relevance: Diabetes mellitus is a multifactorial disease worsening cardiovascular prognosis and prognosis of COVID-19.
Purpose of the study: to assess the features of the clinical course of COVID-19, depending on the presence or absence of hyperglycemia in Uzbekistan.
Materials and methods. Data of questioning of 5023 Tashkent citizens who had COVID-19 between March, 2019 and March, 2021, were analyzed.
Results and discussion. 4.2% of responders had type 1 DM, 15.2% had type 2 DM. 7.9% had newly revealed hyperglycemia needed glucose-lowering treatment. Patients with DM had more severe clinical signs of COVID-19, more of them had pneumonia and needed hospitalization and dexamethasone treatment. Number of lethal outcomes had tendency to increase in all cases of hyperglycemia.
Conclusions: Diabetes mellitus is associated with a worsening of the severity of COVID-19. Patients with diabetes are an older cohort with a higher prevalence of obesity, which can also contribute to a poor prognosis and worsen the acute period of COVID-19

Key words: diabetesmellitus,COVID-19, severity, mortality

First page

190

Last page

194

For citation: Khaydarova F.A., Alimov A.V., Alieva A.V., Khalilova D.Z., Tojieva I.M., Talenova V.A., Alimova N.U., FEATURES OF THE CLINICAL COVID-19 DEPENDING ON THE PRESENCE OR ABSENCE OF HYPERGLYCEMIA ON THE EXAMPLE OF TASHKENT CITY IN 2020 //New Day in Medicine 6(44)2022 190-194 https://clck.bar/L70887

LIST OF REFERENCES:

  1. Roncon L., Zuin M., Rigatelli G., Zuliani G. Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome. //J. Clin. Virol. 127 (2020) 104354. https://doi.org/10.1016/j.jcv.2020.104354
  2. Simonnet A., Chetboun M., Poissy J., Raverdy V., Noulette J., Duhamel A., Labreuche J., Mathieu D., Pattou F., Jourdain M. on behalf of the LICORN and the Lille COVID-19 and Obesity study group. High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation. //J. Obesity (2020) 28, 1195-1199.
  3. Roncon L., Zuin M., Rigatelli G., Zuliani G. Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome. //J. Clin. Virol. 127 (2020) 104354. https://doi.org/10.1016/j.jcv.2020.104354
  4. “Временные рекомендации по ведению пациентов, инфицированных COVID-19 (пятая версия)», Ташкент, 2020 г. – 102 с.
  5. Yan Y., Yang Y., Wang F., Ren H., Zhang Sh., Shi X., Yu X., Dong K. Clinical characteristics and outcomes of patients with severe covid-19 with diabetes. //BMJ Open Diab Res Care 2020;8:e001343. doi:10.1136/ bmjdrc-2020-001343
  6. Shabto J.M., Leah Loerinc L., O’Keefe G.A., O’Keefe J. Characteristics and outcomes of COVID-19 positive patients with diabetes managed as outpatients. //J. Diab. Res. Clin. Pract. 164 (2020) 108229 https://doi.org/10.1016/j.diabres.2020.108229

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