12 — 7 (45) 2022 — Khojiyev D. Y., Karimova M. Sh., CHANGES IN THE MORPHOFUNCTIONAL PROPERTIES OF THE THYROID GLAND AND BLOOD INDICATORS DURING THE HYPOXIC PROCESS INDUCED LUNG FIBROSIS

CHANGES IN THE MORPHOFUNCTIONAL PROPERTIES OF THE THYROID GLAND AND BLOOD INDICATORS DURING THE HYPOXIC PROCESS INDUCED LUNG FIBROSIS

Khojiyev D. Y., Bukhara State Medical Institute named after Abu Ali ibn Sino

Karimova M. Sh., Bukhara State Medical Institute named after Abu Ali ibn Sino

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Throughout a person’s life, the thyroid gland (TG) is exposed to various adverse factors (environmental pollution, drug abuse, bad habits, malnutrition, etc.), which often lead to the development of its pathology. This necessitates the search for new effective means and methods for the prevention and treatment of thyroid dysfunction. During the hypoxic process, changes are observed not only in the morphological structures of the thyroid gland, but also in blood parameters. This process can also include periods of hypoxic state and oncogenesis in the perinatal period, on the basis of which this article analyzes studies of the effect of hypoxic conditions on the morphogenesis of the thyroid gland.

Keywords. thyroid gland, hypoxic state, oncogenesis, hormone.

First page

53

Last page

57

For citation: Khojiyev D. Y., Karimova M. Sh., CHANGES IN THE MORPHOFUNCTIONAL PROPERTIES OF THE THYROID GLAND AND BLOOD INDICATORS DURING THE HYPOXIC PROCESS INDUCED LUNG FIBROSIS /New Day in Medicine 7(45)2022 53-57 https://l.clck.bar/00b2d

LIST OF REFERENCES:

  1. Bil’zhanova G.Zh., Chekurov I.V., Vishnevskaya T.Ya. Morphofunctional profile of the thyroid gland of male Wistar rats in the framework of the experimental model «Hypothyroidism – stress». Izvestiya Orenburgskogo gosudarstvennogoagrarnogo universiteta[Bulletin of the Orenburg State Agrarian University], 2016, no. 2 (58), pp. 177–180. (In Russ.; abstr. in Engl.).
  2. Gel’tser B.I., Zdor V.V., Kotel’nikov V.N. Evolution of views on the pathogenesis of autoimmune diseases of the thyroid gland and the prospects for their targeted therapy. Klinicheskaya meditsina [Clinical Medicine], 2017, Vol. 95, no. 6, pp. 524–534. (In Russ.; abstr. in Engl.).
  3. Тешаев, Ш. Ж., Ширинов, Д. Н., Хожиев, Д. Я., Тухсанова, Н. Э., Камолова, Ш. К., & Тешаев, У. Ш. (2014). Анатомические параметры позвоночного столба у девочек и их связь с параметрами физического развития. //Морфология, 145(3), 193-193.
  4. Kapitonova M.Yu., Fedorova O.V., Nesterova A.A., et al. Stress immunology in early postnatal ontogenesis]. Aktual’nyye voprosy eksperimental’noy i klinicheskoy morfologii: Sbornik nauchnykh trudov[Actual issues of experimental and clinical morphology: collection of scientific proceedings]. Volgograd, 2010, pp. 37–40. (In Russ.; abstr. in Engl.).
  5. Тешаев, Ш. Ж., Ширинов, Д. Н., Хожиев, Д. Я., Тухсанова, Н. Э., Камолова, Ш. К., & Тешаев, У. Ш. (2014). Анатомические параметры позвоночного столба у девочек и их связь с параметрами физического развития. // Морфология, 145(3), 193-193.
  6. Muzhikyan A.A., Ivanov V.S. Features of the histological structure of the dog’s thyroid gland and the morphology of C cells at different stages of ontogenesis. Aktual’nyye voprosy veterinarnoy biologii[Actual problems of veterinary biology], 2015, no. 3 (27), pp. 12–21. (In Russ.; abstr. in Engl.).
  7. Yasenyavskaya A.L., Teplyy D.L. The effect of α-tocopherol on the morphometric parameters of the thyroid gland of white rats in postnatal ontogenesis under conditions of immobilization stress. Astrakhanskiy meditsinskiy zhurnal[Astrakhan Medical Journal], 2013, Vol. 8, no. 1, pp. 329–332. (In Russ.; abstr. in Engl.).
  8. Hong S.H., Braley-Mullen H. Follicular B cells inthyroids of mice with spontaneous autoimmune thyroiditiscontribute to disease pathogenesis and are targets ofanti-CD20 antibody therap. // J. Immunol., 2014, Vol. 192 (3),pp. 897–905.
  9. Yaxshiyevich H. D., Sayfiddinovich A. B. Experimental study of morpho-functional changes in the testes of rats under stress //Web of Scientist: International Scientific Research Journal. – 2021. – Т. 2. – №. 10. – С. 48-54.
  10. Ходорова И., Тешаев Ш.Ж., Хожиев Д.Я., Баймурадов Р.Р., Хасанова Д.А. (2018). Роль инновационных технологий для развития межвузовского сотрудничества по преподаванию предмета «анатомия». ТОМ–II, 297.
  11. Тухсанова Н.Э., Хожиев Д. Я. Роль и место инновационных технологий в тактике обучения в вузе по предмету оперативной хирургии и топографической анатомии //ТОМ–II. – 2018. – С. 264.

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