5 -8 (46) 2022 — M.R.Mamatova, N.N. Zakhirova — GESTATION TROPHOBLASTIK KASALLIKNI ERTA TASHHISLASH VA PROGNOZLASH USULLARINI TAKOMILLASHTIRISH

GESTATION TROPHOBLASTIK KASALLIKNI ERTA TASHHISLASH VA PROGNOZLASH USULLARINI TAKOMILLASHTIRISH

M.R.Mamatova, Andijon Davlat Tibbiyot instituti, Uzbekistan

N.N. Zakhirova Respublika ixtisoslashtirilgan onkologiya va radiologiya ilmiy-amaliy tibbiyot markazi, Toshkent, O‘zbekiston

Rezyume

Ushbu tadqiqotda CLIC-1 proteinining ekspressiyasi gestatsion trofoblastik kasalligida immunogistokimyoviy usul bilan baholandi va malignizatsiya jarayonini prognozlashda uning diagnostik ahamiyati o’rganildi. Tadqiqot gestatsion trofoblastik kasalligi bilan kasallangan 71 ta bemorni o’z ichiga olgan. Yelbo’g’oz bo’lgan bemorlarga nisbatan gestatsion trofoblastik neoplazisi bo’lgan bemorlarda trofoblastik hujayralardagi CLIC-1 ning yuqori darajadagi immunoreaktivligi kuzatildi. Shunday qilib, CLIC-1 erta bosqichda yomon sifatli o’zgarishlarni aniqlash imkonini beradi va prognostik marker bo’lib xizmat qilishi mumkin.

Kalit so’zlar: gestatsion trofoblastik kasalligi, yelbo’g’oz, horiokarsinoma, immunogistokimyo, CLIC-1.

First page

28

Last page

33

For citation: M.R.Mamatova, N.N. Zakhirova GESTATION TROPHOBLASTIK KASALLIKNI ERTA TASHHISLASH VA PROGNOZLASH USULLARINI TAKOMILLASHTIRISH //New Day in Medicine 8(46)2022 28-33 https://clck.ru/sQ52m

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