21 -8 (46) 2022 — Karimov A.X., Tuxtabayev A.A., — EFFECT OF PLACENTAL DYSFUNCTION ON THE FUNCTIONAL STATE OF THE FETAL HEART IN PREGNANT WOMEN WITH COVID-19 ASSOCIATED MYOCARDITIS
EFFECT OF PLACENTAL DYSFUNCTION ON THE FUNCTIONAL STATE OF THE FETAL HEART IN PREGNANT WOMEN WITH COVID-19 ASSOCIATED MYOCARDITIS
Karimov A.X., Department of Obstetrics and Gynecology №2, Tashkent Medical Academy.
Tuxtabayev A.A., Republican Specialized Scientific and Practical Medical Center for Obstetrics and Gynecology of the Ministry of Health of the Republic of Uzbekistan, Tashkent.
Alimova X.P., Republican Specialized Scientific and Practical Medical Center for Obstetrics and Gynecology of the Ministry of Health of the Republic of Uzbekistan, Tashkent.
Tuxtabayeva G.M. State Institution “Zangiota Specialized Hospital No. 1 for the Treatment of Patients with Coronavirus Infection”
Resume
The solution of issues related to placental dysfunction and its complications is the most common problem in modern obstetrics, and this problem is of great importance for the birth of healthy newborns and the reduction of neonatal mortality. In order to confirm the influence of placental disorders causing chronic placental insufficiency and prenatal hypoxia, which developed against the background of COVID-19 associated myocarditis in early gestation, affecting the state of the fetal heart and the development of fetal cardiac pathologies, echocardiography (ECHOCG) and Doppler cardiometry were performed in our study. in the fetus in the III trimester of pregnancy (in the gestational age of 28-36 weeks). As a result of placental dysfunction, there is a violation of a number of processes – worsening energy metabolism in the placenta and fetal tissues, as well as a violation of chemical processes in fetal cardiomyocytes, acidosis, hypoglycemia. As a result, the functioning of the sinus node is inhibited and the contractile function of the myocardium (usually the left sections) is reduced. Transferred intrauterine hypoxia forms by the birth of a child, the syndrome of “disadaptation of the cardiovascular system” (SDSS), which in turn leads to focal myocarditis in the fetus.
Key words: fetal echocardiography, myocarditis during pregnancy, COVID-19 associated myocarditis, fetoplacental dysfunction
First page
115
Last page
120
For citation: Karimov A.X., Tuxtabayev A.A., Alimova X.P., Tuxtabayeva G.M. EFFECT OF PLACENTAL DYSFUNCTION ON THE FUNCTIONAL STATE OF THE FETAL HEART IN PREGNANT WOMEN WITH COVID-19 ASSOCIATED MYOCARDITIS //New Day in Medicine 8(46)2022 115-120 https://clck.ru/sWm7A
LIST OF REFERENCES:
- Bansal M. Cardiovascular Disease and COVID-19 // Diabetes & Metabolic Syndrome: Clinical Research & Reviews. ― 2020. ― Vol. 14. ― P. 247-250
- 2. Е. А. Коган, Ю. С. Березовский, О. В. Благова. Миокардит у пациентов с COVID-19, подтвержденный результатами иммуногистохимического исследования // Кардиология журнал// Том 60, № 7 (2020) doi.org/10.18087/cardio.2020.7.n1209
- Lippi G., M Henry M.B. and Sanchis-Gomar F. Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19) // European Journal of Preventive Cardiology. The European Society of Cardiology. ― 2020 ― 0(0). ― P. 1-3
- Hulot J.S. COVID-19 in patients with cardiovascular diseases // Arch Cardiovasc Dis. ― 2020. ― S1875-2136(20)30080-2. 3. Zheng Y.Y., Ma Y.T., Zhang J.Y., Xie X. COVID-19 and the cardiovascular system // Nat Rev Cardiol. ― 2020. ― 10.1038/ s41569-020-0360-5
- Chan J.F., Kok K.H., Zhu Z. et al. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan // Emerg Microbes Infect. ― 2020.
- Tan W., Aboulhosn J. The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease // Int J Cardiol. ― 2020. ― S0167-5273(20)31593-X.
- Lippi G., Lavie C.J., Sanchis-Gomar F. Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta-analysis [published online] // Prog Cardiovasc Dis [published online]. ― 2020