39 -8 (46) 2022 — Nazarova F.A — CHANGES IN THE CONTENT OF NEUROSPECIFIC PROTEINS IN PREMATURE INFANTS WITH PERINATAL LESIONS OF THE CNS

CHANGES IN THE CONTENT OF NEUROSPECIFIC PROTEINS IN PREMATURE INFANTS WITH PERINATAL LESIONS OF THE CNS

Nazarova F.A. Republican Specialized Scientific and Practical Medical Center of Obstetrics and   Gynecology, Tashkent, Republic of Uzbekistan

Resume

 Perinatal lesion of the central nervous system unites a whole group of lesions of the brain and spinal cord of various causes and origin that occur during pregnancy, childbirth and in the first days of a newborn’s life. From 5 to 55% of children in the first year of life receive such a diagnosis, since this number sometimes includes children with mild transient disorders of the nervous system. Severe forms of perinatal CNS lesions are observed in 1.5–10% of term infants and mainly in 60–70% of premature infants.

Severe perinatal brain lesions such as intracranial hemorrhage, severe cerebral ischemia pose a threat to life and health in premature newborns, even with timely highly qualified medical care.

Moderate and mild forms of brain damage do not pose an immediate threat to life, but they can cause neurological disorders and disorders in the development of motor activity in newborns. At the same time, a special place is occupied by the development of methods for early diagnosis, prevention, treatment of diseases, as well as improving the nursing of premature newborns.

Key words: Procalcitonin, S100β protein, premature infants, hypoxic CNS lesions, autobrain antibodies, hemostasis.

First page

226

Last page

230

For citation: Nazarova F.A CHANGES IN THE CONTENT OF NEUROSPECIFIC PROTEINS IN PREMATURE INFANTS WITH PERINATAL LESIONS OF THE CNS //New Day in Medicine 8(46)2022 226-230 https://clck.ru/sZmJp

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