52 — 8 (46) 2022 — T.V. Tyan., D.A. Alieva., APPROACH TO THE MANAGEMENT OF PATIENTS WITH ENDOMETRIAL HYPERPLASIA AND UTERINE BLEEDING IN POSTMENOPAUSE BASED ON THE ASSESSMENT OF THE PROLIFERATIVE ACTIVITY OF ENDOMETRIAL CELL POPULATIONS

APPROACH TO THE MANAGEMENT OF PATIENTS WITH ENDOMETRIAL HYPERPLASIA AND UTERINE BLEEDING IN POSTMENOPAUSE BASED ON THE ASSESSMENT OF THE PROLIFERATIVE ACTIVITY OF ENDOMETRIAL CELL POPULATIONS

T.V. Tyan., Republican Specialized Scientific and Practical medical center of obstetrics and gynecology

D.A. Alieva., Republican Specialized Scientific and Practical medical center of obstetrics and gynecology

Resume

The spectrum of the histological picture of the endometrium, as well as some markers of the proliferative activity of endometrial cell populations in postmenopausal patients with endometrial hyperplasia and uterine bleeding, were studied. The selection of therapy was carried out based on the somatic and genital status, the results of histological and immunohistochemical studies of the scraping of the uterine cavity. The effectiveness of therapy was assessed by the cessation of bleeding, normalization of hematological parameters, as well as by improving the general well-being of the woman.

Key words: Endometrial hyperplasia, endometrial histology, postmenopausal uterine bleeding, immunohistochemical markers – CD138, p53, Ki67, selection of therapy.

First page

303

Last page

310

For citation:T.V. Tyan D.A. Alieva APPROACH TO THE MANAGEMENT OF PATIENTS WITH ENDOMETRIAL HYPERPLASIA AND UTERINE BLEEDING IN POSTMENOPAUSE BASED ON THE ASSESSMENT OF THE PROLIFERATIVE ACTIVITY OF ENDOMETRIAL CELL POPULATIONS //New Day in Medicine 8(46)2022 303-310 https://clck.ru/vgPsC

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