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  • 85 — 8 (46) 2022 — Abdullaev R.N., A NEW APPROACH TO THE TREATMENT OF SEPSIS IN PURULENT-NECROTIC COMPLICATIONS OF DIABETES MELLITUS

85 — 8 (46) 2022 — Abdullaev R.N., A NEW APPROACH TO THE TREATMENT OF SEPSIS IN PURULENT-NECROTIC COMPLICATIONS OF DIABETES MELLITUS

A NEW APPROACH TO THE TREATMENT OF SEPSIS IN PURULENT-NECROTIC COMPLICATIONS OF DIABETES MELLITUS

Abdullaev R.N., Andijan State Medical Institute

Resume

In order to create a new algorithm in the diagnosis and complex treatment of sepsis in patients with purulent-necrotic complications of diabetes mellitus, studies have been conducted. In the departments of purulent surgery of the ASMI clinic and the regional adult health center of the Andijan region, 180 patients with purulent-necrotic complications of diabetes mellitus underwent research where the tasks were set to create a new algorithm in the diagnosis and complex treatment of sepsis in patients with purulent-necrotic complications of diabetes mellitus in patients with diabetes mellitus, to determine the steps of the algorithm for the application of complex treatment of sepsis and to determine changes in indicators of cellular and humoral protection of the body in patients with diabetes mellitus with manifestations of sepsis. These patients were – diabetic foot – 120 patients, necrotic phlegmon of soft tissues – 40 patients, Fournier’s disease – purulent-necrotic melting of the tissues of the scrotum and perineum – 10 patients and putrefactive processes in the pic.

Key words : Sepsis, diabetes mellitus, purulent-necrotic process

First page

516

Last page

522

For citation: Abdullaev R.N., A NEW APPROACH TO THE TREATMENT OF SEPSIS IN PURULENT-NECROTIC COMPLICATIONS OF DIABETES MELLITUS //New Day in Medicine 8(46)2022 516-522 https://l.clck.bar/37e6d

LIST OF REFERENCES:

  1. Abdullaev R. N. Complex treatment of purulent-necrotic lesions of the lower extremity in patients with diabetic foot syndrome //New Day in Medicine 2(34)2021 https://cutt.ly/qnBEXOw
  2. Abdullayev R.N., Treatment tactics of purulent-necrotic lesions of the lower extremities in diabetes mellitus //New Day in Medicine 6(44)2022 87-94 https://clck.bar/L050de
  3. Абдуллаев Р.Н., Абдуллаева М.А. Новое направление в лечении диабетической стопы//RE-HEALTHJOURNAL. 2022 г.№2(14),с.239-245.
  4. Белобородов В.Б. Сепсис – современная проблема клинической медицины. //РМЖ,2022г. №5.342-355.
  5. Белобородов В.Б. Иммунопатология тяжелого сепсиса и возможности ее коррекции. //”Вестник интенсивной терапии”, 2010 г, №4
  6. Васильев С.В., Лазарев В.М., Дудка В.В., Попов Д.Е. Клинико-диагностические аспекты абдоминального сепсиса в коло проктологической практике //Межрегиональная научно-практическая конференция с международным участием Санкт-Петербургский Cептический форум – 2020. с.141-142
  7. Мусашайхов Х.Т., Икрамова Ф.Д., Василевский Э.А. и др. Пути оптимизации комплексного лечения гнойных заболеваний у больных сахарным диабетом. // “International сonference on educational innovations and applied sciences” 2022/1”. Тошкент. 2022/April 15. Р.116-127.
  8. Мусашайхов Х.Т., Икрамова Ф.Д., Василевский Э.А. и др. Комплексный подход к лечению гнойно-некротических поражений стопы у больных сахарным диабетом // Centralasian journal of medical and natural sciences. 2022. Volume: 03 Issue: 02 | Р.502-504.
  9. Abdullayev R.N. « Peculiarities of treatment of purulent-necrotic complications in patients with diabetic foot syndrome. » // The American Journal of Medical Sciences аnd Pharmaceutical Research (TAJMSPr). Volume 3 Issue 06, 2021, 116-121
  10. Conti P., Ronconi G., Caraffa A., et. al. (2020) Induction of Pro-Inflammatory Cytokines (IL-1 and IL-6) and Lung Inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): Anti-Inflammatory Strategies. // J BiolRegulHomeost Agents, 2020: 34:327-331.
  11. Hotchkiss Richard S., Moldawer Lyle L., Opal Steven M. Sepsis and septic shock. // Nature Reviews Disease Primers. 2016; N 2: 1. P. 1 – 21.
  12. Ramachandran Сirish. Gram-positive and gram-negative bacterial toxins in sepsis // Virulence. 2013; 5 (1). P. 213–218. https://doi.org/10.4161/viru.27024
  13. Shimabukuro-Vornhagen A., Gödel P., Subklewe M., et. al. (2018) Cytokine release syndrome. J Immunother Cancer, 6:56.
  14. Weaver L.K., Behrens E.M. (2017) Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis. Curr Treatm Opt Rheumatol, 3:33-48.
  15. Yiu H.H., Graham A.L., Stengel R.F. (2012) Dynamics of a cytokine storm. PLoSOn, 7:e45027.

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