56 — 9 (47) 2022 — Atoeva M.A., Khayitov A.Kh., PATHOGENETIC BASES OF VIRAL AND BACTERIAL COINFECTIONS IN COVID-19
PATHOGENETIC BASES OF VIRAL AND BACTERIAL COINFECTIONS IN COVID-19
Atoeva M.A., Bukhara State Medical Institute
Khayitov A.Kh., Bukhara State Medical Institute
Resume
This article discusses the main pathogenetic mechanisms for the development of bacterial co-infection in acute respiratory infections and in coronavirus infection. Separate mechanisms were analyzed in detail, including impaired mucociliary clearance, decreased activity of local protective factors of the respiratory mucosa, and impaired antibody production. Modern data on the effect of coronavirus infection on the immune system and interferon production systems are presented, which contributes to the layering of a bacterial infection.
Keywords: coronavirus infection; viral-bacterial co-infections; pathogenic mechanisms, COVID-19
First page
332
Last page
337
For citation: Atoeva M.A., Khayitov A.Kh., PATHOGENETIC BASES OF VIRAL AND BACTERIAL COINFECTIONS IN COVID-19 //New Day in Medicine 9 (47)2022 332-337 https://l.clck.bar/dca5c
LIST OF REFERENCES:
- Атоева М.А., Баратова М.С. Роль ОРВИ и гриппа в формировании осложнений сердечно – сосудистых заболеваний // Фундаментальные и практические вопросы иммунологии и инфектологии: Сб. науч. статей участников Междун. научно – практ. конф. Уфа, – 2018.- С. 35 – 43.
- Abbas M., Robalo Nunes T., Martischang R., Zingg W., Iten A., Pittet D. et al. Nosocomial transmission and outbreaks of coronavirus disease 2019: the need to protect both patients and healthcare workers. // Antimicrob Resist Infect Control. – 2021. – 10. – 7.
- Bakaletz L.O. Viral-bacterial co-infections in the respiratory tract. // Curr Opin Microbiol. – 2017. – 35. – P. 30–35.
- Cole J., Barnard E. The impact of the COVID-19 pandemic on healthcare acquired infections with multidrug resistant organisms. // Am J Infect Control. – 2021. – 49. – 653e4.
- Davis B., Rothrock A.N., Swetland S., Andris H., Davis P., Rothrock S.G. Viral and atypical respiratory co-infections in COVID-19: a systematic review and metaanalysis. // J Am Coll Emerg Phys Open. – 2020.
- Gomez G.B., Mahé C., Chaves S.S. Uncertain effects of the pandemic on respiratory viruses. // Science. – 2021. – Vol. 372, Issue 6546. – P. 1043–1044.
- Hendaus M.A., Jomha F.A. Covid-19 induced superimposed bacterial infection. // J Biomol Struct Dyn. – 2020. – 1–10.
- Katiyar R., Agarwal V., Chowdhary S. et al. Incidence of human rhinovirus coinfection with Staphylococcus aureus among HIV patients suffering from flu like illness. // Int J Pharm Sci Res. – 2017. – 8. – P. 4441–4446.