63 — 9 (47) 2022 — Xamrayev A.A., Yuldasheva D.Kh., Shamsiyeva T.T., Haydarov D.B., DIAGNOSTIC SIGNIFICANCE OF MOLECULAR-GENETIC MARKERS IN THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

DIAGNOSTIC SIGNIFICANCE OF MOLECULAR-GENETIC MARKERS IN THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

Xamrayev A.A., Tashkent Medical Academy, Bukhara State Medical Institute

Yuldasheva D.Kh., Tashkent Medical Academy, Bukhara State Medical Institute

Shamsiyeva T.T., Tashkent Medical Academy, Bukhara State Medical Institute

Haydarov D.B., Tashkent Medical Academy, Bukhara State Medical Institute

Resume

In this article, 98 patients with NAFLD and 70 healthy controls were selected to study the significance of the rs641738 polymorphism of the MBOAT7 gene in the pathogenesis of NAFLD. Our studies confirmed the presence of a positive statistically significant relationship between the rs641738 polymorphism of the MBOAT7 gene and JNAYoX, and this association is especially significant in patients with developed non-alcoholic steatohepatitis.

Key words: non-alcoholic fatty liver disease, hepatic steatosis, non-alcoholic steatohepatitis, rs641738 polymorphism of the MBOAT7 gene

First page

374

Last page

381

For citation: Xamrayev A.A., Yuldasheva D.Kh., Shamsiyeva T.T., Haydarov D.B., DIAGNOSTIC SIGNIFICANCE OF MOLECULAR-GENETIC MARKERS IN THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE //New Day in Medicine 9 (47)2022 374-381 https://l.clck.bar/4ca02

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