10 -10 (48) 2022 — Kh.Z. Akhmedzhanova., X.N. Tursunova., — STATE OF OVARIAN RESERVE IN WOMEN OF LATE REPRODUCTIVE AGE

STATE OF OVARIAN RESERVE IN WOMEN OF LATE REPRODUCTIVE AGE

Kh.Z. Akhmedzhanova., Tashkent Medical Academy

X.N. Tursunova., Tashkent Medical Academy

F.I. ShukurovTashkent Medical Academy

Resume

Objective: to assess the state of the ovarian reserve in women of late reproductive age and to develop innovative ways to restore fertility.

Material and methods. 130 women of late reproductive age were examined. Depending on the age, the patients were divided into 2 groups: 50 women aged 36-39 years (Group 1) and 50 women aged 40-44 years (Group 2). The comparison group consisted of 30 women of early reproductive age with normal ovarian reserve. All patients underwent a complex of general clinical, laboratory and instrumental studies. To assess the state of the ovarian reserve, all patients underwent determination of the concentration of anti-Mullerian hormone in the blood serum and counting the number of antral follicles in each ovary.

Results. It was found that the content of the biochemical marker of ovarian reserve AMH was reduced by 2.7 times in 55% of women, and by 3.1 times in 45% of women. A decrease in the echographic marker of AFC ovarian reserve was found in 55% of women by 2.2 times and by 2.4 times in 45% of women.

Conclusion. The results of the study allow us to assess the situation as extremely serious, since among the markers of ovarian reserves in women of late reproductive age, the content of AMH increased by 2.7 times in 55% of women, by 3.1 times in 45% of women. women, and the content of AFC by 2.2 times in 55% of women, and in 45% of women it was found that it decreased by 2.4 times. The current situation requires the development of differentiated innovative methods to increase the ovarian reserve in order to restore fertility in this category of women.

Key words: late reproductive age, ovarian reserve, anti-Müllerian hormone, antral follicle count

First page

52

Last page

56

For citation:Kh.Z. Akhmedzhanova., X.N. Tursunova., F.I. Shukurov STATE OF OVARIAN RESERVE IN WOMEN OF LATE REPRODUCTIVE AGE //New Day in Medicine 10(48)2022 52-56 https://clck.ru/32RHyy

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