36 -10 (48) 2022 — Salaeva Z.Sh. — CLINICAL-ANAMNESTIC AND IMMUNOPHENOTYPING ANALYSIS OF CHILDREN’S LYMPHOCYTIC LEUKEMIA

CLINICAL-ANAMNESTIC AND IMMUNOPHENOTYPING ANALYSIS OF CHILDREN’S LYMPHOCYTIC LEUKEMIA

Salaeva Z.Sh.Urgench branch of Tashkent Medical Academy,  Urgench, Uzbekistan

Resume

Our studies  have shown that in order to conduct a clinical and anamnestic analysis of lymphocytic leukemia in children, the following examination plan is drawn up. It will be necessary to conduct a general blood analysis, a puncture of the sternum, an immunophenotyping method to determine the subpopulation of B and T lymphocytes, and an immunohistochemical examination to detect blast lymphocytes.

In this scientific study, immunophenotyping was conducted in 22 patients with acute lymphoblastic leukemia, diagnosed at the Republican Hematology Center. According to the results of the investigation, the leukemic blasts of acute lymphoblastic leukemia (ALL), consisting of V-lymphocyte precursors, were found to have a large number of immunophenotypic aberrations. The changes in the bone marrow and lymphoid organs, which morphologically determine the acute and chronic forms of lymphocytic leukemia in children, serve as a fundamental basis in the scientific and practical activities of clinical doctors.

Key words: Children, leukemia, lymphoid leukemia, bone marrow, spleen, lymph node

First page

204

Last page

207

For citation:Salaeva Z.Sh. – CLINICAL-ANAMNESTIC AND IMMUNOPHENOTYPING ANALYSIS OF CHILDREN’S LYMPHOCYTIC LEUKEMIA //New Day in Medicine 10(48)2022 204-207 https://clck.ru/32WNXD

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