21 -1 (33) 2021 — Koyirov A.K., Boltayev E.B. — NON-INVASIVE LUNG VENTILATION IN ACUTE RESPIRATORY FAILURE CAUSED BY NEW CORONAVIRUS INFECTION COVID-19

NON-INVASIVE LUNG VENTILATION IN ACUTE RESPIRATORY FAILURE CAUSED BY NEW CORONAVIRUS INFECTION COVID-19

Koyirov A.K. -Republican Specialized Center Zangiota N:1 Bukhara State Medical Institute.

Boltayev E.B. -Republican Specialized Center Zangiota N:1 Bukhara State Medical Institute.

Shirinov D.K. -Republican Specialized Center Zangiota N:1 Bukhara State Medical Institute.

Rakhimov M.M. -Republican Specialized Center Zangiota N:1 Bukhara State Medical Institute.

Jalilov A.A. -Republican Specialized Center Zangiota N:1 Bukhara State Medical Institute.

Resume

Relevance. Treatment of acute respiratory distress syndrome caused by coronavirus infection remains an urgent problem in the world community.Objective of the study: Improving the results of treatment of patients with acute respiratory failure by differentiated use of non-invasive ventilation methods.Material and methods: In the intensive care unit of the Zangiot infectious diseases hospital No. 1 from 08.2020 to 11.2020, 124 patients with COVID-19 and complicated acute respiratory failure were examined, of which 68 were men and 56 women. The male to female ratio was 4: 3. The patients’ age is from 67 to 87 years. (average age 60.8 ± 4.8).The patients were divided into three groups depending on the type of respiratory therapy.As a result of the study, the tidal volume (TO) was 319.59 ± 7.74 ml in the CPAP mode and 329.47 ± 7.15 ml in the DUAL-LEVEL mode. On the third day, DO increased by 18.8% in CPAP mode and by 23.2% in DUAL- LEVEL mode. In phase III of the study, DO increased in both groups and increased to 521.31 ± 13.83 ml in the CPAP mode and to 583.77 ± 15.37 ml in the DUAL-LEVEL mode, that is, in the DUAL-LEVEL mode, the DO was by 10 , 6% higher than in CPAP mode.Conclusion: Both modes of non-invasive pulmonary ventilation give positive clinical results, improve indicators of central hemodynamics, normalize blood gas composition and parameters of external respiration. In this case, DUAL-LEVEL mode is much more effective than CPAP mode.

Key words: COVID-19, acute respiratory failure, non-invasive ventilation, external respiration

First page

107

Last page

114

For citation: Koyirov A.K., Boltayev E.B.,Shirinov D.K., Rakhimov M.M., Jalilov A.A Non-invasive lung ventilation in acute respiratory failure caused by new coronavirus infection covid-19//New Day in Medicine 1(33)2021 107-114 https://cutt.ly/nzlySdM

LIST OF REFERENCES:

  1. World Health Organization. Global surveillance for human infection with coronavirus disease (COVID-2019). 2020. Available at: https://www.who.int/publications detail/globalsurveillance-for-human-infection- with-novel-coronavirus- (2019-ncov) [Accessed: May 17, 2020].
  2. Spina S., Marrazzo F., Migliari M. et al. The response of Milan’s Emergency Medical System to the COVID-19 outbreak in Italy. Lancet. 2020; 395 (10227): E49-50. DOI: 10.1016 / S0140-6736 (20) 30493-1.
  3. Ruan Q., Yang K., Wang W. et al. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020; 46 (5): 846-848. DOI: 10.1007 / s00134-020-05991-x.
  4. Richardson S., Hirsch J. S., Narasimhan M. et al. Presenting characteristics, comorbidities, and outcomes among 5,700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020; 323 (20): 2052-2059. DOI: 10.1001 / jama.2020.6775.
  5. Zhu N., Zhang D., Wang W. et al. A novel coronavirus from patients with pneumonia in China, 2019. N. Engl. J. Med. 2020; 382: 727–733. DOI: 10.1056/NEJMoa2001017.
  6. Wu Z., McGoogan J.M. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020; 323 (13): 1239– 1242. DOI: 10.1001/jama. 2020.2648.
  7. Rochwerg B., Brochard L., Elliott M.W. et al. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur. Respir. J. 2017; 50 (2): 1602426. DOI: 10.1183/13993003.02426-2016.
  8. Avdeev S.N. [Noninvasive ventilation  in acute respiratory failure: from clinical guidelines to the real clinical practice. Commentary on Clinical guidelines on use of noninvasive ventilation in patients with acute respiratory failure]. Pulmonologiya. 2018; 28 (1): 32–35. DOI: 10.18093/0869-0189- 2018- 28-1-32-35 (in Russian).

file

download