31 -2 (52) 2023 — Kasymov A.L., Mansurov Sh.Sh. — EXPERIMENTAL EVALUATION OF THE EFFICIENCY OF LOCAL INTRAOPERATIVE HEMOSTASIS DURING THYROID SURGERY

EXPERIMENTAL EVALUATION OF THE EFFICIENCY OF LOCAL INTRAOPERATIVE HEMOSTASIS DURING THYROID SURGERY

Kasymov A.L., Andijan State Medical Institute Uzbekistan, Andijan, st. Yu. Atabekova Experimental laboratory of the Republican Specialized Scientific and Practical Medical Center for Surgery named after academician V.V.Vakhidov

Mansurov Sh.Sh., Andijan State Medical Institute Uzbekistan, Andijan, st. Yu. Atabekova Experimental laboratory of the Republican Specialized Scientific and Practical Medical Center for Surgery named after academician V.V.Vakhidov

Usmonov E.I., Andijan State Medical Institute Uzbekistan, Andijan, st. Yu. Atabekova Experimental laboratory of the Republican Specialized Scientific and Practical Medical Center for Surgery named after academician V.V.Vakhidov

Sadykov R.A.,Andijan State Medical Institute Uzbekistan, Andijan, st. Yu. Atabekova Experimental laboratory of the Republican Specialized Scientific and Practical Medical Center for Surgery named after academician V.V.Vakhidov

Butabaev J.M. Andijan State Medical Institute Uzbekistan, Andijan, st. Yu. Atabekova Experimental laboratory of the Republican Specialized Scientific and Practical Medical Center for Surgery named after academician V.V.Vakhidov

Resume

The article presents the results of experimental studies on the possibility of using local intraoperative hemostasis in thyroid surgery. The experiments were carried out in the laboratory of the State Institution “RSNPMCH named after academician V. Vakhidov” on male rats weighing 320-350 g in the amount of 24 individuals. Two groups of experimental animals were formed, in control, only the effect of a bipolar coagulator with a hemostatic purpose was studied, in the experimental group, the use of a hemostatic agent Hemoben and laser exposure was studied. In order to assess the effect of hemostasis, an extended resection was performed not only of the left lobe of the thyroid gland, but also of the left and lower submandibular lymphatic and salivary glands. The study showed that Hemoben powder retains its hemostatic properties for a long time when incisions are made in the experimental neck area. This allows for the management and prevention of bleeding during operations on organs and tissues with a high risk of bleeding in the neck. Laser irradiation provides in the postoperative period an early onset of regression of the inflammatory process and a decrease in the risk of formation of adhesions and scars.

Key words: experimental model, thyroid gland, bipolar coagulation, chemobene, local hemostasis, laser irradiation.

First page

179

Last page

188

For citation: Kasymov A.L., Mansurov Sh.Sh., Usmonov E.I., Sadykov R.A.,Butabaev J.M. – EXPERIMENTAL EVALUATION OF THE EFFICIENCY OF LOCAL INTRAOPERATIVE HEMOSTASIS DURING THYROID SURGERY //New Day in Medicine 2(52)2023 179-188 https://clck.ru/33bdhz

LIST OF REFERENCES:

1. Бликян КМ. Орган сберегающие операции при узловых образованиях щитовидной железы /Автореф. канд.мед.наук.– 14.00.27; – 2019; Ростов на Дону. 20 с
2. Гринцов АГ, Матийцив АБ, Ахрамеев ВБ, Гринцов ГА, Пилюгин ГГ. Меры предупреждения интраоперационных кровотечений при больших и гигантских доброкачественных новообразованиях щитовидной железы //Таврический медико-биологический вестник 2021;24(2):35-39.
3. Калинин РЕ, Сучков ИА, Базаев СБ, Крылов АА. Локальные гемостатические средства в хирургической практике. Журнал им. Н.В. Склифосовского Неотложная медицинская помощь. 2021;10(2):337–346. https://doi.org/10.23934/2223-9022-2021-10-2-337-346
4. Кваченюк АН, Гулько ОН., Супрун ИС, Негриенко КВ. Применение электросварочной технологии как основного метода диссекции и гемостаза в эндокринной хирургии //Ендокринологія’ 2017;22(3)262-266.
5. Лебедева ДВ, Ильичева ЕА, Григорьев ЕГ. Современные аспекты хирургического лечения диффузного токсического зоба //Сибирский медицинский журнал (Иркутск), 2019;3:28-35.
6. Романчишен АФ. Ургентные хирургические вмешательства при заболеваниях щитовидной железы и осложнениях раннего послеоперационного периода //Педиатр. 2013;4:103-115.
7. Усманов ИС, Курганов ИА, Емельянов СИ, Мамиствалов МШ, Лукьянченко ДВ. Факторы, влияющие на интраоперационную безопасность при эндоскопических операциях на щитовидной железе. //Эндоскопическая хирургия. 2022;28(6):53‑63.
8. Шидловский АВ, Дейкало ИН, Шидловский ВА, Осадчук ДВ, Пелешок ОИ. Сравнительная оценка результатов операций на щитовидной железе, выполненных традиционным методом и с использованием технологии liga sure // Сучаснi медичнi технології, 2013;3:235-237.
9. Canu GL, Medas F, Cappellacci F, Casti F, Bura R, Erdas E, Calò PG. The Use of Harmonic Focus and Thunderbeat Open Fine Jaw in Thyroid Surgery: Experience of a High-Volume Center. //J Clin Med. 2022;29:11(11):3062. doi:10.3390/jcm11113062. PMID:35683450; PMCID: PMC9181533.
10. Ekici M, Zeren S, Yíldírím Ali, Yaylak, Faik, Arık, Özlem DEVECİ, Uğur ALGIN, Mustafa. (2020). T., Cerrahisinde oksitlenmiş selüloz kullanımının postoperatif hipokalsemi üzerine etkisi. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi. 10.17517/ksutfd.794176.
11. Iliff HA, El-Boghdadly K, Ahmad I, Davis J, Harris A, Khan S, Lan-Pak-Kee V, O’Connor J, Powell L, Rees G, Tatla TS. Management of haematoma after thyroid surgery: systematic review and multidisciplinary consensus guidelines from the Difficult Airway Society, the British Association of Endocrine and Thyroid Surgeons and the British Association of Otorhinolaryngology, Head and Neck Surgery. Anaesthesia. 2022 Jan;77(1):82-95. doi: 10.1111/anae.15585. Epub 2021 Sep 21. PMID: 34545943; PMCID: PMC9291554
12. Moran K, Grigorian A, Elfenbein D, Schubl S, Jutric Zeljka, Lekawa M., Nahmias J. (2020). Energy vessel sealant devices are associated with decreased risk of neck hematoma after thyroid surgery. Updates in Surgery. 72. 10.1007/s13304-020-00776-9