52 -1 (33) 2021 — Rahmonov N.H., Abdurahmonov M.M., — IMMUNOLOGICAL SHIFTS IN PATIENTS WITH CHEST AND ACUTE BLOOD LOSS

IMMUNOLOGICAL SHIFTS IN PATIENTS WITH CHEST AND ACUTE BLOOD LOSS

Rahmonov N.H. -Bukhara State Medical Institute

Abdurahmonov M.M. -Bukhara State Medical Institute

Abdurahmonov Z.M. -Bukhara State Medical Institute

Resume

The research is dedicated to the investigation of some defensive functions in patients under severe combined trauma and acute blood loss, including blood level of cortisol and pro-inflammatory – TNF-α. Venous blood of patients or healthy volunteers was investigated. The concentrations of TNF-α in blood was increased in patients of all groups. It has been revealed that a low blood cortisol level in the 1st day under severe combined trauma was an unfavorable sign for prognosis, witnessing high probability of lethal outcome. The results open a possibility for implementation of a highly informative test-system for prognosis of traumatic disease course and for its purposeful correction.

Key words: immune response, severe combined trauma, acute blood loss, shock, stress, cytokines, cortisol.

First page

273

Last page

276

For citation: Rahmonov N.H Abdurahmonov M.M Abdurahmonov Z.M. Immunological shifts in patients with chest and acute blood loss//New Day in Medicine 1(33) 2021 273-276 https://cutt.ly/kx0DZuk

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