16 -3 (53) 2023 — Fayzillaeva G. I. Abdullaeva M. A. — DRUG  LIVER DAMAGE AS THE MAIN FACTOR OF POST-COVID 19 COMPLICATIONS

DRUG  LIVER DAMAGE AS THE MAIN FACTOR OF POST-COVID 19 COMPLICATIONS

Fayzillaeva G. I. Bukhara State Medical Institute named after Abu Ali ibn Sina Uzbekistan Bukhara

Abdullaeva M. A. Bukhara State Medical Institute named after Abu Ali ibn Sina Uzbekistan Bukhara

Resume

The pandemic of coronavirus infection COVID-19, although today it has almost become endemic, is fraught with many long-term side effects, such as liver damage. But the question arises whether it is true that it is the coronavirus infection that is the main cause of damage to this organ or many hepatotoxic substances lead to complications. In this article, we will analyze many studies conducted in different countries of the world. There are cytotoxic lesions leading to the development of acute or chronic hepatitis, cholestatic lesions associated with structural changes in the elements of the biliary system or the mechanisms of bile formation. Morphological features of lipid metabolism disorders in hepatocytes with the development of hepatic steatosis and steatohepatitis are also described. In some cases, under the influence of drugs, damage to the intrahepatic vasculature, accumulation of pigments, development of granulomatous reactions and liver fibrosis are observed.

Key words: biliary excretion process, occurrence of jaundice without signs of an obstructive component, drug-induced liver injury, factors of post-COVID complications in COVID-19

First page

87

Last page

91

For citation: Fayzillaeva G. I. Abdullaeva M. A. – DRUG  LIVER DAMAGE AS THE MAIN FACTOR OF POST-COVID 19 COMPLICATIONS //New Day in Medicine 3(53)2023 87-91 https://goo.su/kbxBN

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