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  • 56 -1 (33) 2021 — Narzullaev N.U., Radjabov A.Kh., CYTOKINE STATUS IN DISEASES OF THE UPPER RESPIRATORY TRACT IN CORONAVIRUS DISEASE (COVID-19)

56 -1 (33) 2021 — Narzullaev N.U., Radjabov A.Kh., CYTOKINE STATUS IN DISEASES OF THE UPPER RESPIRATORY TRACT IN CORONAVIRUS DISEASE (COVID-19)

CYTOKINE STATUS IN DISEASES OF THE UPPER RESPIRATORY TRACT IN CORONAVIRUS DISEASE (COVID-19)

Narzullaev N.U. -Bukhara State Medical Institute

Radjabov A.Kh. -Bukhara State Medical Institute

Mirzoyeva M.R. -Bukhara State Medical Institute

Resume

The data of own examinations of 123 patients with laboratory and clinical and epidemiologically confirmed new coronavirus infection and inflammatory diseases of the upper respiratory tract are presented. The content of hemoglobin, the number of erythrocytes, the concentration of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor alpha (TNF-α) and C-reactive protein (CRP) were studied. It was shown that in patients with novel coronavirus infection (COVID-19) and inflammatory diseases of the upper respiratory tract, the average values ​​of the degree of saturation of hemoglobin with oxygen were 87.04%. Anemia was detected in 8.9% of examinations, an increase in CRP of more than 5 mg / l was noted in 81 (65.8%) patients. In 19 patients, in 24.3% of cases, the level of cytokines in the blood serum was assessed before the start of antibiotic therapy. At the same time, the content of IL-6 was increased in 17 (89.4%) patients. Demonstrated a positive correlation between the content of C-reactive protein and the level of TNF-α.

Key words: coronavirus; COVID-19; upper respiratory tract; cytokines; interleukin-10; interleukin-6; tumor necrosis factor-alpha; cytokine storm.

First page

291

Last page

299

For citation: Narzullaev N.U., Radjabov A.Kh., Mirzoyeva M.R. Cytokine status in diseases of the upper respiratory tract in coronavirus disease (covid-19)//New Day in Medicine 1(33)2021 291-299 https://cutt.ly/Sx4Mj5x

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