28 -4 (54) 2023 — Kurbaniyazova M.Z., Duschanova Z.A. — IMPROVEMENT OF OVARIAN STIMULATION IN WOMEN WITH POLYCYSTOSIS OVARIAN SYNDROME

IMPROVEMENT OF OVARIAN STIMULATION IN WOMEN WITH POLYCYSTOSIS OVARIAN SYNDROME

Kurbaniyazova M.Z., Urgench branch of the Tashkent Medical Academy, Uzbekistan

Duschanova Z.A. Urgench branch of the Tashkent Medical Academy, Uzbekistan

Resume

The authors evaluated the efficacy of letrozole and clomiphene citrate in combination with human menopausal gonadotropin (hMG) in clomiphene citrate-resistant infertile women with PCOS.

Combination with hMG is one of the most effective methods in women with clomiphene citrate resistant polycystic ovary syndrome and prevents complications such as ovarian hyperstimulation syndrome and multiple pregnancies.

Keywords: polycystic ovary syndrome, clomiphene citrate resistance, letrozole, clomiphene citrate, ovarian hyperstimulation syndrome, human menopausal gonadotropin (hMG).

First page

142

Last page

146

For citation: Kurbaniyazova M.Z., Duschanova Z.A. – IMPROVEMENT OF OVARIAN STIMULATION IN WOMEN WITH POLYCYSTOSIS OVARIAN SYNDROME //New Day in Medicine 4(54)2023 142-146 https://goo.su/AL4Pw0i

LIST OF REFERENCES:

  1. Адамян Л.В., Андреева Е.Н., Абсатарова Ю.С., Григорян О.Р., Дедов И.И., Мельниченко Г.А., Сутурина Л.В., Филиппов О.С., Шереметьева Е.В., Чернуха Г.Е., Ярмолинская М.И. Клинические рекомендации “Синдром поликистозных яичников”. Проблемы Эндокринологии. 2022;68(2):112-127. https://doi.org/10.14341/probl12874
  2. Доброхотова Ю. Э., Матризаева Г.Д., Курбаниязова М.З., Дусчанова З.А., Сапарбаева Н.Р., Икрамова Х.С. Евразийский вестник педиатрии, 2020;2(5):43-49 [Dobroxotova Yu. E’., Matrizaeva G.D., Kurbaniyazova M.Z., Duschanova Z.A., Saparbaeva N.R., Ikramova X.S. Evrazijskij vestnik pediatrii, 2020;2(5):43-49]. https://cutt.ly/DveOv0M;
  3. Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society. American Association of Clinical Endocrinologists, American College Of Endocrinology, And Androgen Excess and Pcos Society Disease State Clinical Review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome – part 2. // Endocr Pract. 2015 Dec;21(12):1415-26.
  4. Zafarjanovna, Kurbaniyazova Madina, and Bekbauliyeva Gulistan Niyetbayevna. “Optimization of ovulation induction methods in infertil women with PCOS.” // In Euro-Asia Conferences, 2021;1(1):158-162.
  5. Zafarjanovna, Kurbaniyazova Madina, Bekbauliyeva Gulistan Niyetbayevna, and Duschanova Zaynab Atabayevna. “Optimization of Ovulation Induction in Clomifene Resistant Patient with Infertility.” // Biomedical Journal of Scientific & Technical Research  2021;39(2):31257-31259.
  6. Zafarjanovna K.M., Niyetbayevna B.G., Rakhimbayevna S.N., Tulibayevna R.D., Pirzhanova I.N. Optimization of treatment for women with infertility. International Journal of Health Sciences, 2022;6(S2):94-99. https://doi.org/10.53730/ijhs.v6nS2.4977
  7. Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41-47.
  8. Zeinalzadeh M., Basirat Z., Esmailpour M. Efficacy of letrozole in ovulation induction compared to that of clomiphene citrate in patients with polycystic ovarian syndrome //The Journal of reproductive medicine. 2010;55(1-2):36-40.
  9. Franik S., Eltrop S.M., Kremer J.A., Kiesel L., Farquhar C. Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. // Cochrane Database of Systematic Reviews. 2018; doi:10.1002/14651858.cd010287.pub3

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