74 -4 (54) 2023 — Zoitova N.M. — PREPARING COUPLES FOR IVF WITH DIFFERENT FERRITIN LEVELS
PREPARING COUPLES FOR IVF WITH DIFFERENT FERRITIN LEVELS
Zoitova N.M. Tashkent Medical Academy
Resume
Ferritin is a marker of iron resources and is vital to the body6. It has a pro-oxidant effect associated with oxidative stress and inflammation9. A low level of ferritin indicates iron deficiency anemia, and an increase in its level indicates the presence of inflammation and high levels of oxidative stress. All of these corollary factors associated with changes in ferritin levels have a significant impact on fertility1.
In this study, we evaluated the effect of changing the level of ferritin in patients included in the IVF/ICSI protocol at the IVF Center “Cis on Bulacis”. The purpose of this study is a comparative analysis of the effect of changing the level of ferritin on the number and quality of retrieved oocytes, as well as embryos during IVF/ICSI protocols. Thus, changes in ferritin levels can impair the quality of oocytes and embryos, resulting in poor growth and development and reduced chances of a successful pregnancy.
Key words: IVF/ICSI, oocyte and embryo quality, ferritin, latent iron deficiency.
First page
396
Last page
400
For citation: Zoitova N.M. – PREPARING COUPLES FOR IVF WITH DIFFERENT FERRITIN LEVELS //New Day in Medicine 4(54)2023 396-400 https://goo.su/REMsXz
LIST OF REFERENCES:
- Tonai S, Kawabata A, Nakanishi T, et al. Iron deficiency induces female infertile in order to failure of follicular development in mice. // J Reprod Dev. 2020;66(5):475. doi:10.1262/JRD.2020-074
- Inhorn MC, Patrizio P. Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century. // Hum Reprod Update. 2015;21(4):411-426. doi:10.1093/HUMUPD/DMV016
- Deroux A, Dumestre-Perard C, Dunand-Faure C, Bouillet L, Hoffmann P. Female Infertility and Serum Auto-antibodies: a Systematic Review. // Clin Rev Allergy Immunol. 2017;53(1):78-86. doi:10.1007/S12016-016-8586-Z/METRICS
- Joham AE, Palomba S, Hart R. Polycystic Ovary Syndrome, Obesity, and Pregnancy. // Semin Reprod Med. 2016;34(2):93-101. doi:10.1055/S-0035-1571195
- Sinai Talaulikar V, Bajoria R, Ehidiamhen A., Mujawar E, Chatterjee R. P-587 Does iron overload affect ovarian reserve? – A 10-year longitudinal study of evaluation of ovarian reserve in women with transfusion-dependent beta thalassaemia major. // Hum Reprod. 2022;37(Supplement_1). doi:10.1093/HUMREP/DEAC107.541
- Search Results | Human Reproduction | Oxford Academic. Accessed March 23, 2023. https://academic.oup.com/humrep/search-results?page=1&q=Effect of Ferritin on IVF Outcomes&fl_SiteID=5285&SearchSourceType=1&allJournals=1
- Abstract book of the 31 st ESHRE Annual Meeting, Lisbon, Portugal, 14–17 June 2015 . Hum Reprod. 2015;30(suppl 1):i1-i501. doi:10.1093/HUMREP/30.SUPPLEMENT_1.1
- Moshinsky M. No Titleیلیب. Vol 13.; 1959.
- Sanchez AM, Papaleo E, Corti L, et al. Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones. // Hum Reprod. 2014;29(3):577-583. doi:10.1093/HUMREP/DET466
- Mensi L, Borroni R, Reschini M, et al. Oocyte quality in women with thalassaemia major: insights from IVF cycles. // Eur J Obstet Gynecol Reprod Biol X. 2019;3. doi:10.1016/J.EUROX.2019.100048
- Teede HJ, Misso ML, Costello MF, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. // Fertil Steril. 2018;110(3):364. doi:10.1016/J.FERTNSTERT.2018.05.004
- Bartke A. Embryology. // Hum Reprod. 1996;11(suppl_1):148-157. doi:10.1093/HUMREP/11.SUPPL_1.148
- Inhorn MC, Patrizio P. Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century. // Hum Reprod Update. 2015;21(4):411-426. doi:10.1093/HUMUPD/DMV016