93 -5 (55) 2023 — Sabirova Sh.G., Karimov Kh.Ya. — ANALYSIS OF CHIMERIC ONCOGENES BCRABL P210 AND BCRABL P190 IN SOME TYPES OF HEMATOLOGICAL CANCER PATIENTS IN UZBEKISTAN

ANALYSIS OF CHIMERIC ONCOGENES BCRABL P210 AND BCRABL P190 IN SOME TYPES OF HEMATOLOGICAL CANCER PATIENTS IN UZBEKISTAN

Sabirova Sh.G., Republican Specialized Scientific and Practical Medical Center of Hematology, Tashkent

Karimov Kh.Ya., Republican Specialized Scientific and Practical Medical Center of Hematology, Tashkent

Boboev K.T. Republican Specialized Scientific and Practical Medical Center of Hematology, Tashkent

Resume

The study was conducted on the basis of the Republican Center for Scientific and Practical Medicine of Specialized Hematology, it involved 101 patients (including 6 children and adolescents and 95 adults) admitted to the oncology department of the center. The study concluded that the incidence of the disease among males and females was slightly higher in men than in women. Also, in particular, in all patients with В-ALL, T-ALL and AML, BCR-ABLP190 was equal to 0%, and only in patients with CML of various variants of the BCR-ABL oncogene (BCR-ABLP210, BCR-ABLP190) a mutation was found.

Key words: gene, chronic myeloid leukemia, polymerase chain reaction, analysis, patients.

First page

527

Last page

532

For citation: Sabirova Sh.G., Karimov Kh.Ya., Boboev K.T. – ANALYSIS OF CHIMERIC ONCOGENES BCRABL P210 AND BCRABL P190 IN SOME TYPES OF HEMATOLOGICAL CANCER PATIENTS IN UZBEKISTAN //New Day in Medicine 2023 5(55): 527-532 https://newdaymedicine.com/index.php/2023/06/16/l-157/

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