100 -5 (55) 2023 — Juraboeva G.B., Pulatova Sh.B. — MARKERS OF KIDNEY FIBROSIS EVALUATION IN RHEUMATOID ARTHRITIS DISEASE

MARKERS OF KIDNEY FIBROSIS EVALUATION IN RHEUMATOID ARTHRITIS DISEASE

Juraboeva G.B., Tashkent Medical Academy

Pulatova Sh.B., Tashkent Medical Academy

Agzamova G.S. Tashkent Medical Academy

Resume

Renal dysfunction was studied in patients with rheumatoid arthritis.    According to him, depending on the clinical stage, duration of the disease and increasing age, kidney damage was more determined.   Renal damage was more common in seropositive rheumatoid arthritis patients.   The relationship between TGF-β1 and cystatin-S, which are markers of fibrosis, was studied in groups of patients, and it was confirmed that glomerular filtration rate (GFR), which is a criterion for assessing the functional state of the kidneys, decreases with the increase in the amount of both markers in the blood.  

Key words: Rheumatoid arthritis, kidney damage, TGF-β1, Cystatin-S, chronic kidney disease.  

First page

573

Last page

578

For citation: Juraboeva G.B., Pulatova Sh.B., Agzamova G.S. – MARKERS OF KIDNEY FIBROSIS EVALUATION IN RHEUMATOID ARTHRITIS DISEASE //New Day in Medicine 2023 5(55): 573-578 https://newdaymedicine.com/index.php/2023/06/16/l-164/

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