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  • 16 -6 (56) 2023 — Ismoilova Z.A., Axmedjanova N.I. — CORRELATION BETWEEN CYTOKINE PROFILE AND PARTIAL RENAL FUNCTION IN ACUTE RENAL PATHOLOGY DURING COVID-19 IN CHILDREN

16 -6 (56) 2023 — Ismoilova Z.A., Axmedjanova N.I. — CORRELATION BETWEEN CYTOKINE PROFILE AND PARTIAL RENAL FUNCTION IN ACUTE RENAL PATHOLOGY DURING COVID-19 IN CHILDREN

CORRELATION BETWEEN CYTOKINE PROFILE AND PARTIAL RENAL FUNCTION IN ACUTE RENAL PATHOLOGY DURING COVID-19 IN CHILDREN

Ismoilova Z.A., Urgench branch of the Tashkent Medical Academy Uzbekistan

Axmedjanova N.I. Samarkand State Medical University Uzbekistan

Resume

The lesion of tubule cells as a key event in the formation of tubulointerstitial disorders, stimulates the excretion of proinflammatory cytokines and growth factors by these cells and indicates a significant role of the latter as local mediators. All children with a history of Covid-19 had significantly increased levels of TNF-a, y-INF, and IL-4 in serum and urine. There was a strong correlation between these cytokines and titratable acidity, ammonia excretion, nonspecific inflammatory markers, erythrocyturia, leukocyturia, indicating the need to study TNF-a, y-INF and IL-4 as local inflammatory stimulation factors in the renal tissue.

Keywords. Cytokines, tubular cells, correlation, acute tubulointerstitial nephritis, acute pyelonephritis

First page

98

Last page

102

For citation: Ismoilova Z.A., Axmedjanova N.I. – CORRELATION BETWEEN CYTOKINE PROFILE AND PARTIAL RENAL FUNCTION IN ACUTE RENAL PATHOLOGY DURING COVID-19 IN CHILDREN //New Day in Medicine 2023 6(56): 98-102 https://newdaymedicine.com/index.php/2023/06/13/l-130/

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