• Home
  • NEW DAY MEDICINE
  • 6(56)2023
  • 75 -6 (56) 2023 — Qoyirov A.K., Boltayev E.B. — THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA IN TRAUMA SURGERY

75 -6 (56) 2023 — Qoyirov A.K., Boltayev E.B. — THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA IN TRAUMA SURGERY

THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA IN TRAUMA SURGERY

Qoyirov A.K., Republican Scientific Center for Emergency Medical Care

Boltayev E.B. Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Currently, one of the urgent problems in anesthesiology is safe and adequate sedation in regional anesthesia. According to the basic principles of modern anesthesiology, safe and effective sedation should ensure the protection of the patient’s psycho-emotional sphere, the absence of awakening, the absence of pain and fear, the absence of nausea and vomiting in the postoperative period; at the same time, it should not cause respiratory depression and influence on hemodynamics, and should not be accompanied by a delayed recovery of psychomotor function. After studying the current literature and analyzing our own observations, we came to the conclusion that under conditions of regional anesthesia, sedation with dexmedetomidine is preferable, rather than propofol. Sedation with Dexmedetomidine leads to a decrease in the incidence of cognitive impairment in the early postoperative period, a decrease in the intensity of pain, a beneficial effect on recovery and activation after surgery, and is also associated with a lower incidence of hypoxemia and hypotension during surgery.

Keywords: sedation, regional anesthesia, dexmedetomidine.

First page

439

Last page

443

For citation: Qoyirov A.K., Boltayev E.B. – THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA IN TRAUMA SURGERY //New Day in Medicine 2023 6(56): 439-443 https://newdaymedicine.com/index.php/2023/07/06/l-244/

LIST OF REFERENCES:

  1. Svetlov V.A., Zaytsev A.Yu, Kozlov S.P. Balanced anesthesia based on regional blockades: strategy and tactics [Sbalansirovannaya anesteziya na osnove regionarnykh blokad: strategiya i taktika]. Anesteziologiya i reanimatologiya. 2006;4:4–33. [In Russian]
  2. Precedex (dexmedetomidine). Hospira, Inc., Lake Forest, IL 60045 USA. Available from: http://medlibrary.org/lib/rx/ meds/precedex/page/1–7
  3. Candiotti K.A., Bergese S.D., Bokesch P.M., Feldman M.A., Wisemandle W., Bekker A.Y. Monitored Anesthesia Care with Dexmedetomidine: A Prospective, Randomized, Double-Blind, Multicenter Trial. Anesthesia & Analgesia [Internet]. Ovid Technologies (Wolters Kluwer Health); 2010 Jan;110(1):47–56. Available from: https://doi. org/10.1213/ane.0b013e3181ae0856
  4. Bergese S.D., Candiotti K.A., Bokesch P.M., Zura A., Wisemandle W., Bekker A.Y. A Phase IIIb, Randomized, Double-blind, Placebo-controlled, Multicenter Study Evaluating the Safety and E‡cacy of Dexmedetomidine for Sedation During Awake Fiberoptic Intubation. American Journal of Therapeutics [Internet]. Ovid Technologies (Wolters Kluwer Health); 2010 Nov;17(6):586–95. Available from:https://doi.org/10.1097/mjt.0b013e3181d69072
  5. Wu W., Chen Q., Zhang L., Chen W. Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy. Journal of International Medical Research [Internet]. SAGE Publications; 2014 Feb 10;42(2):516–22. Available from: https://doi.org/10.1177/0300060513515437
  6. Ebert T.J., Hall J.E., Barney J.A., Uhrich T.D., Colinco M.D. The E†ects of Increasing Plasma Concentrations of Dexmedetomidine in Humans. Anesthesiology [Internet]. Ovid Technologies (Wolters Kluwer Health); 2000 Aug;93(2):382– 94. Available from: https://doi.org/10.1097/00000542– 200008000–00016
  7. Krasenkova E.A., Ovechkin A.Y., Pyregov A.V. Inˆuence of anesthetic techniques on occurrence of postoperative cognitive dysfunction in elderly patients undergoing gynecologicalsurgery. Bulletin of Russian State Medical University [Internet]. Pirogov Russian National Research Medical University; 2016;(4):51–5. Available from: https://doi. org/10.24075/brsmu.2016–04–08
  8. Karelov А.E., Lebedinskiy K.M., Buravtsov V.I. Anesthetic, analgetic, hypnotic – are the dentitions important?. Anesteziologii I Reanimatologii, 2015;12(5):3–11. [In Russian]
  9. Kulikov А.S., Lubnin А.Yu. Dexmedetomidine: new opportunities in the anesthesiology. Anesteziologiya i Reanimatologiya. 2013;(1):37–41. [In Russian]
  10. Хайитов Д.Х., Болтаев Э.Б. (2022). Постреанимацион касаллик натижасида келиб чикадиган асоратларни бартараф этишда замонавий интенсив терапия. Клиник амалиетда учраган холат. Academic research in modern science, 2022;1(9):172-178.
  11. Yarashev A.R., Boltaev E.B., Shabaev Y.K. A retrospective analysis of complications of percutaneous dilated tracheostomy // New day in medicine, 2020;4(32):301-304.
  12. Boltayev E.B., Sabirov J.M. Organization of oxygen therapy using a nasal mask and ventura mask in severe patients with Covid-19 corona virus infection. Eme. Jou. Edu. Dis.Lif. Lea. [Internet], 2021Aug. 24 [cited 2021 Oct.17]; 2(08):6-10.
  13. Khayotovich K.D., Bekmurodugli B.E. (2022). Case in clinical practice: Modern intensive care in the treatment of post-resuscitation complications caused by cardiac arrhythmias. ACADEMICIA: An International Multidisciplinary Research Journal.
  14. Boltayev E.B. Choice of respiratory therapy in severe patients with new coronavirus infection covid-19 // Achievements of science and education. Founders: Olympus. 2020;8:70-74.
  15. Koyirov A.K. et al. Non-invasive lung ventilation in acute respiratory failure caused by new coronavirus infection Covid-19 // New Day in Medicine, 2021;1:107-114.
  16. Shodmonovov, J. B. (2023). Conduct respiratory therapy in patients with severe coronavirus infection. Eurasian Research Bulletin, 2023;20:12-17.
  17. Qoyirov A.Q., Azimov A.A., Boltayev E.B. (2022). The Role of High-Flow Ventilation in the Treatment of Acute Respiratory Failure. //Eurasian Research Bulletin, 2022;15:89-101.
  18. Болтаев Э.Б. (2022, October). Ўткир нафас етишмовчилиги билан асоратланган янги коронавирус инфекцияси COVID-19да ноинвазив ўпка вентиляцияси. In problems of modern surgery, international scientific and practical conference with the participation of foreign scientists materials. Андижанский государственный медицинский институт.
  19. Boltayev Elmurod Bekmurod ugli. (2023). Choice of respiratory therapy in severe patients with new coronavirus infection COVID-19. Eurasian Research Bulletin, 20, 18–22. Retrieved from https://geniusjournals.org/index.php/erb/article/view/4107
  20. Ураков Ш.Т., Эшонов О.Ш., Болтаев Э.Б. Послеоперационная когнитивная дисфункция. Новый день в медицине. 2019;2(26):56–60. ID: 44647992.

file

download