27 -9 (59) 2023 — Ruzieva Z.I. — FREQUENCY OF NEONATAL ATELECTASIS OF THE LUNG AND MORPHOLOGICAL CHANGES
FREQUENCY OF NEONATAL ATELECTASIS OF THE LUNG AND MORPHOLOGICAL CHANGES
Ruzieva Z.I. Tashkent Medical Academy
Resume
The aim of this study was to address the problems of lung tissue changes in atelectasis. Primary atelectasis of the lungs “enters the respiratory distress syndrome and appears as a separate nosological unit. In this article, specific pathomorphological signs of primary lung atelectasis are studied. As a material, the lungs of babies who died of atelectasis in the neonatal period were studied microscopically. In the results of the microscopic examination, it was found that the lung tissue has an underdeveloped appearance at first glance.
It is observed that the tissue between the alveoli consists of dense tissue and cellular tufts, the blood vessels are wide and full, and it has a structure around which blood clots have appeared. Macrophages, neutrophils, and migrated alveolocytes are detected in the alveolar space. After 7-10 days, it is determined that alterative-proliferative processes escalated and turned into atelectatic pneumonia. As a result, pneumosclerosis, bronchiectasis, and the transformation of bronchi into retention cysts are observed. Often, at the site of atelectasis, connective tissue grows and sclerosing develops.
Keywords: infant, lung, distress syndrome, primary atelectasis newborn infants, atelectasis, respiratory failure syndrome.
First page
144
Last page
152
For citation: Ruzieva Z.I. – FREQUENCY OF NEONATAL ATELECTASIS OF THE LUNG AND MORPHOLOGICAL CHANGES //New Day in Medicine 2023 9(59): 144-152 https://newdaymedicine.com/index.php/2023/09/12/l-365/
LIST OF REFERENCES:
- Birkun A.A., Zagogulko A.K., Phuc Phat et al. The state of lung surfactant in their immaturity. Archives of Pathology. 1990;2:10-14.
- Bogdan I.Y. Respiratory therapy of severe forms of RDS in deep premature babies in the early neonatal period. Dissertation, Candidate of Medical Sciences, M., 2000.
- Bubnova N.I. Artificial ventilation and bronchopulmonary dysplasia in children with low body weight. – Intensive therapy in obstetrics and neonatology: Theses of reports of the I Congress of obstetricians and gynaecologists of the Turkmen SSR, Ashgabat, 1988;41-43.
- Vanovskaya I.V. Complications of artificial lung ventilation in children. (Literature review). Voprosy zashchita maternosti i detstva. 1996;21(1):75-77.
- Volodin H.H., Degtyarev D.N. Principles of nursing children with extremely low body weight. //Issues of obstetrics and gynaecology 2003;2:64-70
- Glukhovets B.I. Gaivoronsky I.V. et al. Pathogenetic features of respiratory distress syndrome in newborns with extremely low body weight // Archives of Pathology. 2005:67(1.):3-5.
- Grebennikov V.A. Evaluation of the haemodynamic effect of dopamine in newborns with SDR. Bulletin of the USSR Academy of Medical Sciences, 1984;9:77-80.
- Dementieva G.M., Kuzmina T.B., Baleva L.S. et al. Repeated and chronic bronchopulmonary diseases at an early age in children on artificial ventilation in the neonatal period. Ros. Bulletin of gynecology and pediatrics. 1997;1:21-24.
- Evseev S.F., Kutyavin A.A., Stolovich M.N. Risk factors for the development of bronchopulmonary dysplasia during artificial lung ventilation in newborns // Emergency conditions in children: Mat. of VI congress. VI congress. Paediatricians of Russia. M, 2021;107.
- Evtyukov G.M. Syndrome of respiratory disorders in newborns // Problems of human health formation in the perinatal period and in childhood: Collection of scientific works, ed. by N.P. Shabalov. – St.P: Public. “Olga”, 2020;172-178.
- Kuznetsova N.F., Tuzakina U.B., Charushnikova G.A. Features of phospholipid metabolism in women who gave birth to children with respiratory distress syndrome. – Voprosy zashchita maternosti i detstva. 2011;2:21-54.
- Liubsys A. Immaturity of the lungs: neonatal perspective -development of the lung. Journal of obstetrics and female diseases. St.Peterburg. 1999;99.
- American Academy of Pediatrics.Committee on Fetus and Newborn. Surfactant replacement therapy for respiratory distress syndrome.-Pediatrics, 1991;87(6):946-947
- Dorsi M. Pediatric constitutional therapy // Kinderarztl. Prex, 1993;61(1):24-27.
- Forster R. E. Respiratory physiology and lunglipid metabolism. Ann. Rev. Physiol., 2005;47:751.
- Gibson R.L., Jackson J.C., Twiggs G.A. Bronchopulmonary dysplasia: survival after prolonged mechanical ventilation. // Am. J.Dis.Child., 1988;42:721-732.