26 -2 (34) 2021 — Abdurakhmanov M.M., Saidova L.B., — MECHANISMS OF HEMOSTASIOLOGICAL REACTIONS AND DYSFUNCTION OF THE VASCULAR WALL ENDOTHELIUM IN PATIENTS WITH ACUTE ACETIC ACID POISONING

MECHANISMS OF HEMOSTASIOLOGICAL REACTIONS AND DYSFUNCTION OF THE VASCULAR WALL ENDOTHELIUM IN PATIENTS WITH ACUTE ACETIC ACID POISONING

Abdurakhmanov M.M., Bukhara State Medical Institute, Bukhara branch of RSCEMP.

Saidova L.B., Bukhara State Medical Institute, Bukhara branch of RSCEMP.

Kuvatov Z.Kh. Bukhara State Medical Institute, Bukhara branch of RSCEMP.

Resume

One of the formidable complications of acetic acid poisoning is prolonged intravascular coagulation syndrome (DIC). Many of the key mechanisms of this syndrome remain unexplored. The functional activity of platelets (Tr) and endothelium was investigated. The activity of Tr was determined by the parameters of their aggregation, the function of the endothelium – by the activity of von Willebrand factor (VWF) and the number of desquamated endothelial cells (DEC). It was found that the greatest changes were observed in patients with severe poisoning and were characterized by Tr hypoaggregation, increased EF activity and an increase in the amount of DHEC.

Key words: acetic acid poisoning, hemostasiology, functional activity of platelets, endothelial function.

First page

132

Last page

135

For citation: Abdurakhmanov M.M., Saidova L.B., Kuvatov Z.Kh Mechanisms of hemostasiological reactions and dysfunction of the vascular wall endothelium in patients with acute acetic acid poisoning //New Day in Medicine 2(34)2021 132-135 https://cutt.ly/cb0eTLJ

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