28 -2 (34) 2021 — Khamdamov B. Z., Dehkanov A. T. — PROSPECTS FOR THE USE OF SILVER PREPARATIONS FOR THE LOCAL TREATMENT OF WOUND INFECTION

PROSPECTS FOR THE USE OF SILVER PREPARATIONS FOR THE LOCAL TREATMENT OF WOUND INFECTION

Khamdamov B. Z., Bukhara State Medical Institute.  

Dehkanov A. T. Bukhara Regional Multidisciplinary Medical Center.

Resume

 Cytomorphological studies have revealed that a differentiated approach with the use of a two-component ointment based on silver ions combined with Povidone-iodine, taking into account the phase of the wound process in the treatment of wound infection, in contrast to traditional methods of treatment, has a number of positive aspects. In particular, the wound is cleared of infection by 2,0-2,5 days faster, the process of transition of the wound process from phase I to phase II is accelerated by 2,5-3,0 days, already on the 4-5 day of treatment, the cytological picture is replaced by an inflammatory-regenerative type of cytogram, which is characteristic of the uncomplicated course of the inflammatory process, and the number of purulent-necrotic, dysregenerative complications in the wound, which contributes to rapid scarring and epithelization of its surface.

Key words: wound infection, Povidone-iodine, two-component silver preparations

First page

141

Last page

146

For citation: Khamdamov B. Z., Dehkanov A. T. Prospects for the use of silver preparations for the local treatment of wound infection //New Day in Medicine 2(34)2021 141-146 https://cutt.ly/Wb0eHAo

LIST OF REFERENCES

  1. Askarov T.A., Khamdamov B.Z., Khamdamov I.B. Improvement of methods of complex treatment of purulent-necrotic lesions of the foot in diabetes mellitus // Journal of Theoretical and Clinical Medicine. -2015. – No. 1. – S. 73-76.
  2. Bubenchikova V.N., Malyutkina A.Yu. Morphological characteristics of the course of the wound process in the treatment of an experimental infected wound with a gel based on a thick extract of the herb speckled herb. // Electronic journal: Modern problems of science and education. 2013.S. 33-37.
  3. Blatun L.A. Local drug treatment of wounds. Surgery. // Journal them. N.I. Pirogova 2011; (4): 51-9.
  4. Grigoryan A.Yu., Bezhin A.I., Pankusheva T.A. Some antiseptics in the treatment of purulent wounds. // International Academic Bulletin 2014; (4): 6-8.
  5. Rodin A.V., Privolnev V.V., Barsukov A.N. Possibilities of using silver sulfathiazole for local treatment of wound infection. // Outpatient surgery. 2018, 1-2 (69-70). – S.42-50.
  6. Obolensky V.N., Ermolov A.A. Local negative pressure method in the prevention and treatment of wound infections. // Journal of Medical Alphabet №7 / 2017, volume №1. Emergency medicine pp. 18-22.
  7. Okhunov A.O., Pulatov U.I., Okhunova D.A. Morphological characteristics of the course of the wound process in purulent-inflammatory diseases of soft tissues against the background of diabetes mellitus // Bulletin of Science and Education 2018, No. 9 (45) P. 72-77.
  8. Privolnev V.V., Zabrosaev V.S., Danilenkov N.V. Silver preparations in the local treatment of infected wounds. // Journal of the Bulletin of the Smolensk State Medical Academy. 2015, Volume 14, No. 3. S. 85-91.
  9. Samtsov A.V., Telichko I.N., Statsenko A.V. The use of external agents containing silver compounds in the treatment of patients with pyoderma. // Bulletin of Dermatology and Venereology. 2014.1: 75-80.
  10. Supilnikov A.A., Grigorieva Yu.V., Devyatkin A.A. Morphological picture of the course of the wound process in the anterior abdominal wall with experimental damage // Bulletin of the medical institute “REAVIZ” 2016 No. 4. S. 26-32.
  11. Khamdamov B.Z. Method of laser photodynamic therapy in the treatment of wound infection in diabetic foot syndrome. // Biology va tibbiyot muammolari. – 2020. -№1 (116) – pp. 142-148.
  12. Hamdamov B.Z., Nuraliev N.A., Teshaev Sh.Zh., Gaziev K.U., Hamdamov I.B. Experimental development of methods for local treatment of wound infection. // Problems of Biology and Medicine. – 2020, No. 1 (116). – S. 194-199.
  13. Khamdamov B.Z. Optimization of methods of local treatment of purulent-necrotic lesions of the foot in diabetes mellitus // Journal “New Day in Medicine”. – 2018. – No. 4 (24) – S. 112-115.
  14. Brook I. Spectrum and treatment of anaerobic infection and //Chemotherapy, 2016. Vol. 22 №1 P. 1-13.
  15. Sutterlih S, Dahlo M. High freguency of silver resistence genes in invasive iso-lates of Enterobacter and Klebsiella species. //J Hosp Infect. 2018, 96 (3): 256-261.
  16. Khamdamov B. Z., Nuraliev N.A. Pathogenetic approach in complex treatment of diabetic foot syndrome with critical lower limb ischemia //American Journal of Medicine and Medical Sciences. -2020 10 (1) – P. 17-24. DOI: 10.5923/j.20201001.05.
  17. Portillo M.E., Salvado M., Alier A., Martinez S., etal. Advantages of sonication fluid culture for the diagnosis of prosthetic joint infection. //J Infect.2014;Vol.69:35–41.doi:.10.1016/ j.jinf.2014.03.002.

file

download