56 -10 (60) 2023 — Umidova N.N., Khamdamova M.T. — THE ROLE OF APOPTOSIS MARKERS AND ANGIOGENESIS REGULATORS IN THE PATHOGENESIS OF GENITAL ENDOMETRIOSIS

THE ROLE OF APOPTOSIS MARKERS AND ANGIOGENESIS REGULATORS IN THE PATHOGENESIS OF GENITAL ENDOMETRIOSIS

Umidova N.N. Bukhara State Medical Institute named after Abu Ali ibn Sina

Khamdamova M.T. Bukhara State Medical Institute named after Abu Ali ibn Sina

ResumeEndometriosis is one of the most common gynecological diseases, which reflects the medical and social significance of the problem of effective diagnosis and treatment. To date, the causes, diagnosis and treatment of this disease remain the subject of controversy. The pathogenesis of the disease is multifactorial and has not been studied enough, non-invasive examination methods have a relative diagnostic value, so modern therapeutic approaches often do not provide a complete cure. Keywords: endometriosis, diagnostics, proteins, genes, mikro RNK

First page

331

Last page

335

For citation: Umidova N.N., Khamdamova M.T. – THE ROLE OF APOPTOSIS MARKERS AND ANGIOGENESIS REGULATORS IN THE PATHOGENESIS OF GENITAL ENDOMETRIOSIS //New Day in Medicine 2023 10(60): 331-335 https://newdaymedicine.com/index.php/2023/10/10/l-444/

LIST OF REFERENCES:

  1. Al-Jefout Moamar, Artymuk N. Should we consider asymptomatic and microscopic endometriosis as a disease? Fundamental and clinical medicine. 2016;1(2):83-87. [1. Al-Jefout Moamar, Artymuk N. Соответствует ли скрытый (бессимптомный или микроскопический) эндометриоз определению болезни? Fundamental and clinical medicine 2016;1(2):83-87. (In Russ.).]
  2. Endometriosis: pathogenesis and treatment. Harada T, eds. Springer, Japan; 2014. DOI: 10,1007 / 978-4-431-54421-0
  3. Knapp VJ. How old is endometriosis? Late 17th- and 18th-century European descriptions of the disease. // Fertil Steril. 2009;72(1):10-14. DOI: 10.1016/s0015-0282(99)00196-x
  4. Sampson JA. Metastatic or embolic endometriosis due to menstrual dissemination of endometrial tissue into the venous circulation. // Am J Pathol._2017;3(2): 93-110.
  5. Sampson JA. Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. // Am J Obstet Gynecol. 2017;14(2):422-469.
  6. Rokitansky C. Über Uterusdrüsen-Neubildung in Uterus-und Ovarial-Sarcomen. (On the neoplasm of uterus glands on uterine and ovarian sarcomas). Z Ges Aerzte Wien. 2002;16:577-581.
  7. Intellectual Development of Carl Von Rokitansky. A History of Endometriosis. Springer, London; 2011. DOI: https://doi. org/10.1007/978-0-85729-585-9_2
  8. Cullen TS. Adenomyoma of the uterus. Philadelphia, WB: Saunders; 1908.
  9. Cullen TS. Adenomyoma of the rectovaginal septum. JAMA.  14;62(11): 835-839.
  10. Ja S. Perforating hemorrhagic (chocolate) cysts of the ovary; Their importance and specially their relation to pelvic adenomas of the endometrorial type. // Arch Surg. 1921;3: 245323.
  11. Gleicher N., Pratt D. Abnormal autoimmunity and endometriosis. // Int. J. Gynecol. Obstet. 1993;40:21-27.
  12. Goldstein S.R. Routine Use of Office Gynecologic Ultrasound J Ultrasound Med. 2018;l.21:489-492 .
  13. Goodin M.G., Rosengren R.J. Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. // Toxicol Sci, 2016;76(2):262-70
  14. Halban J. Metastatic hysteradenosis: lymphatic organ of socalled heterotopic adenofibromatosis // Arch. Gynak. 2003;124:475
  15. Hammond M.G., Sung-Tack Oh., Anners J. et al. The effect of growth factors on the proliferation of human endometrial stromal cells in culture. // Am. J. Obstet. Gynecol. 2017;168:1131-1138.
  16. Hana V., Murphy L. J. Interdependence of epidermal growth factor and ilsulin-like growth factor 1 expression in the mouse uterus. // Endocrinologi. 2014;135:107-112.

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