62 -10 (60) 2023 — Tosheva D.R. — TREATMENT OF DRUG-RESISTANT SPINE TUBERCULOSIS USING A COMBINATION OF SURGICAL INTERVENTION AND INDIVIDUAL CHEMOTHERAPY

TREATMENT OF DRUG-RESISTANT SPINE TUBERCULOSIS USING A COMBINATION OF SURGICAL INTERVENTION AND INDIVIDUAL CHEMOTHERAPY

Tosheva D.R. Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Tuberculosis continues to be one of the most common infections in the world and poses a serious threat to public health. The disease continues to be a complex socioeconomic, medical and biological problem. The problem in recent years has been that tuberculosis has become characterized by a high tendency to progression, rapid development of the cavity and multiresistance of Mycobacterium tuberculosis (MBT) to anti-tuberculosis drugs.

Key words: Mycobacterium tuberculosis, isoniazid, katG mutations, ethionamide, prothionamide, GeneXpert, MDR, XDR, rifampicin.

First page

369

Last page

372

For citation: Tosheva D.R. – TREATMENT OF DRUG-RESISTANT SPINE TUBERCULOSIS USING A COMBINATION OF SURGICAL INTERVENTION AND INDIVIDUAL CHEMOTHERAPY //New Day in Medicine 2023 10(60): 369-372 https://newdaymedicine.com/index.php/2023/10/10/l-450/

LIST OF REFERENCES;

1. Tosheva Dilnoza Rakhmatovna, Features of Drug Resistance of the Causative Agent of Tuberculosis in Modern Conditions, // Амалий ва тиббиёт фанларининг илмий журнали, 2023;2(4):59-63.
2. Tosheva Dilnoza Rakhmatovna,Causal Relationship of Immuno-Microbiological Parameters in Tuberculosis With Multiple and Broad Drug Resistance,  // International Journal of Health System and Medical Science, 2020;2(5).
3. Tosheva Dilnoza Rakhmatovna, Особенности лекарственной устойчивости возбудителя туберкулеза в современных условиях, // Амалий ва тиббиёт фанларининг илмий журнали, 2023;2(2):52-58.
4. Tosheva Dilnoza Rakhmatovna, Helicobacter pylori in children with gastric dyspepsia syndrome. // Journal of Advanced Research and Stability, 2022;2(3).
5. Tosheva Dilnoza Rakhmatovna, Helicobacter Pylori and the Risk of Coronary Heart Disease (Literature Review) // International Journal of Innovative Analyses and Emerging Technology 2021;1(4).
6. Tosheva Dilnoza Rakhmatovna,  Enterobiosis in Children Current Diagnostic Problems  // European multidisciplinary journal of modern science, https://emjms.academicjournal.io/index.php/ Volume: 7
7. Mansurova M. Kh., Nazarov J.-S. E. Features of clinical manifestation of brucellosis // New Day in Medicine. Bukhara, 2021;1(33):184-189.
8. Абдуллаев Р.Ю., Комиссарова О.Г., Чумакова Е.С., Одинец В.С. Уровень мочевой кислоты в сыворотке крови у больных впервые выявленным туберкулезом легких с множественной лекарственной устойчивостью возбудителя // Туберкулёз и болезни лёгких 2017;95(4):31-36.
9. Аксенова В.А., Клевно Н.И., Кавтарашвили С.М., Казаков А.В., Пахлавонова А.Д. Очаг туберкулезной инфекции как риск развития туберкулеза у детей с множественной лекарственной устойчивостью возбудителя // Туберкулёз и болезни лёгких. 2018;96(1):11-17.
10. Андреевская С.Н., Смирнова Т.Г., Ларионова Е.Е., Андриевская И. Ю., Черноусова Л.Н., Эргешов А. Изониазид-резистентные Mycobacterium tuberculosis: частота выявления, спектры резистентности и генетические детерминанты устойчивости // Вестник РГМУ. – 2020;1:22-28.