89 -10 (60) 2023 — Yuldasheva D.Х., Radjabov N.G. — DIAGNOSTIC VALUE OF CLINICAL AND LABORATORY MARKERS IN NON-ALCOHOLIC FATTY LIVER DISEASE

DIAGNOSTIC VALUE OF CLINICAL AND LABORATORY MARKERS IN NON-ALCOHOLIC FATTY LIVER DISEASE

Yuldasheva D.Х., Bukhara State Medical Institute named after Abu Ali ibn Sina

Radjabov N.G. Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This article studied clinical and laboratory analyzes of 98 patients with non-alcoholic fatty liver disease (NAFLD). With steatohepatitis, higher ALT and AST values ​​are noted than in patients with hepatic steatosis. The main differential difference between non-alcoholic steatosis and steatohepatitis, available in clinical practice, may be the severity of the biochemical syndrome of cytolysis. The article contains clinical features and prognosis in patients with fatty hepatosis and non-alcoholic steatohepatitis (NASH). Dyslipidemia (hypertriglyceridemia, decreased HDL, increased LDL) occurs in about 65-85% of patients. The basal insulin level, according to the results of our studies, in persons with NAFLD at the stage of steatosis and steatohepatitis was significantly increased.

Key words: non-alcoholic fatty liver disease, liver steatosis, non-alcoholic steatohepatitis, insulin resistance, obesity, lipoprotein, cholesterol, alanine aminotransferase.

First page

526

Last page

533

For citation: Yuldasheva D.Х., Radjabov N.G. – DIAGNOSTIC VALUE OF CLINICAL AND LABORATORY MARKERS IN NON-ALCOHOLIC FATTY LIVER DISEASE //New Day in Medicine 2023 10(60): 526-533 https://newdaymedicine.com/index.php/2023/12/01/l-553/

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