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  • 113 -10 (60) 2023 — Yuldashev B.A. — STRUCTURAL AND MORPHOLOGICAL CHANGES OF MYOCARDIUM IN CHILDREN WITH CHRONIC KIDNEY DISEASE

113 -10 (60) 2023 — Yuldashev B.A. — STRUCTURAL AND MORPHOLOGICAL CHANGES OF MYOCARDIUM IN CHILDREN WITH CHRONIC KIDNEY DISEASE

STRUCTURAL AND MORPHOLOGICAL CHANGES OF MYOCARDIUM IN CHILDREN WITH CHRONIC KIDNEY DISEASE

Yuldashev B.A. Samarkand State Medical University

Resume

Chronic kidney disease (CKD) in children is associated with increased cardiovascular risk. Cardiovascular complications account for more than 30% of all deaths in pediatric patients with end-stage CKD. The pathological process is based on the influence of renal pathology on structural and morphological changes in the heart muscle. Morphological studies of the myocardium were carried out on autopsy material from 28 deceased children suffering from chronic kidney disease, and the development of polymorphic pathomorphological changes in cardiomyocytes was detected.

Key words: chronic kidney disease, children, morphology, myocardium, cardiomyocyte.

First page

667

Last page

671

For citation: Yuldashev B.A. – STRUCTURAL AND MORPHOLOGICAL CHANGES OF MYOCARDIUM IN CHILDREN WITH CHRONIC KIDNEY DISEASE //New Day in Medicine 2023 10(60): 667-671 https://newdaymedicine.com/index.php/2023/12/26/l-672/

LIST OF REFERENCES:

  1. Савенкова Н.Д., Григорьева О.П. Педиатрические проблемы стратификации тяжести стадий, сердечно-сосудистых осложнений и почечного прогноза хронической болезни почек по классификациям NKF-K/DOQI (2002) и KDIGO (2012). // Нефрология. 2021; 25 (3): 9-19. doi: 10.36485/1561-6274-2021-25-3-9-19
  2. Lilien MR, Groothoff JW. Cardiovascular disease in children with CKD or ESRD. // Nat Rev Nephrol2009;5(4):229-235. doi: 10.1038/nrneph.2009.10.
  3. Mitsnefes M.M. Cardiovascular disease in children with chronic kidney disease. // J Am Soc Nephrol (JASN)2012; 23(4):578–585. doi: 10.1681/ASN.2011111115
  4. Haddad MN, Winnicki E, Nguyen S. Editors. Adolescents with Chronic Kidney Disease from Diagnosis to End-Stage Disease. // Springer. 2019; https://doi.org/10.1007/978-3-319-97220-6
  5. Weaver DJ, Mitsnefes M. Cardiovascular disease in children and adolescents with chronic kidney disease. // Semin Nephrol 2018;38(6):559–569.doi.org/10.1016/j.semnephrol. 2018.08.002
  6. Mitsnefes MM, Betoco A, Schneider MF, et al. FGF23 and left ventricular hypertrophy in children with CKD. // Clin J Am Soc Nephrol 2018;13(1):45–52. doi: 10.2215/CJN.02110217
  7. Vishwanath VN and Karan VN.  Cardiac changes in patients of chronic kidney disease. // International Journal of Advanced Research in Medicine 2021; 3(1):253-256. doi: https://doi.org/10.22271/27069567.2021.v3.i1e.145
  8. Яковцова И.И., Топчий И.И., Данилюк А.Н. и др. Морфологические особенности строения аорты, коронарных артерий и миокарда при хронической болезни почек у детей. // Медичні науки. Scientific Journal «ScienceRise» 2015; 12/3(17):66-71. doi:10.15587/2313 8416.2015.57234
  9. K/DOQI Kidney Disease Outcomes Quality Initiative. Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification Stratification. // Am J Kidney Dis (AJKD)2002;39(2) Suppl.1:1–266. doi: 10.1016/S0272-6386(02)70101-7

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