47 -2 (34) 2021 — Sharipova O.A., Mamatkulova D.Kh., — CONTENT OF GONADOTROPIC HORMONES AND TESTOSTERONE IN BLOOD SERUM IN PATIENTS WITH CHRONIC LUNG DISEASES

CONTENT OF GONADOTROPIC HORMONES AND  TESTOSTERONE IN BLOOD SERUM IN PATIENTS  WITH CHRONIC LUNG DISEASES

Sharipova O.A., Samarkand Medical Institute. Uzbekistan

Mamatkulova D.Kh., Samarkand Medical Institute. Uzbekistan

Abdurakhmonov Zh.N. Samarkand Medical Institute. Uzbekistan

Resume

The assessment of sexual development and the study of the hormonal status in the blood serum in patients with chronic lung diseases (CLD). The study included 140 children with CLD. The results of the study showed a significant difference in the time of the onset of pubertal changes, the intensity of the development of secondary sexual characteristics (VPP), as well as functional disorders in the pituitary gland system, which was characterized by an increase in FSH concentration, a decrease in LH and a decrease in testosterone in boys with CLD. In girls with CLD, there was no significant predominance of FSH levels at the beginning of puberty, the LH content throughout puberty was significantly lower, and the level of estradiol was significantly low in older age groups.

Thus, CLD negatively affects the sexual development of children, which dictates the need to develop certain practical measures in this direction.

Keywords:  chronic chronic lung diseases, sexual development, blood hormones.

First page

238

Last page

242

For citation:Sharipova O.A., Mamatkulova D.Kh., Abdurakhmonov Zh.N. Content of gonadotropic hormones and  testosterone in blood serum in patients  with chronic lung diseases //New Day in Medicine 2(34)2021 238-242 https://cutt.ly/PngLLdH

LIST OF REFERENCES

1. Astafieva N.G. “Medical and social examination of adolescents with chronic lung diseases. // Russian Bulletin of Perinatology and Pediatrics, N:6, 2003, p. 22-26.
2. Bogdanova A.V. et al. Epidemiological aspects of chronic diseases of small bronchi in children. // Bulletin of modern clinical medicine, 2015, volume 8, N:. 2.- P.43-50.
3. Blinova I.M., Botvinyeva V.V. Characteristics of bilateral chronic pneumonia in children. (Proceedings of the 7th National Congress on Respiratory Diseases: Abstracts. Report – Moscow. 1997. – P. 232.
4. Sharipova О.А., Bobomuratov Т.А., Turaeva N.О. Evaluation of sexual development in patients with bronchiectatic disease // XXIXth International Scientific and Practical Conference “International scientific review of the problems and prospects of modern science and education”. – Boston, 2016. № 21 (31) – pp. 74–76.
5. Iskandarova Sh.T. Physical development and morbidity of adolescents living in Tashkent // Pediatrics. 2003, S. 10-12.
6. Mamatkulova D.Kh., Sharipova O.A. Treatment algorithm for chronic obstructive lung disease. Innovative development of science and education. International scientific and practical conference June 2020 Kazakhstan, pp. 55-56
7. Prakhin E.I., Gritsinskaya V.L. Characteristics of methods for assessing the physical development of children. // Pediatrics 2004, no. 2 p. 60-62.
8. Ulanova L.N. and others. On the standardization of indicators of puberty in children and adolescents // Pediatrics 1981. №4. P. 70-72.
9. Bobomuratow T.A., Sharipova O.A., Mamatkulova D.X., Bakhronov Sh.S. Features of sexual development statejf the pituare-gonad system and measures of secondare prevention in sick children with chronic bronchitis. International Iornal of Pharmaceutical Research. 377-381.2020.
10. 10.Yende S., Waterer G.W., Tolley E.A. et al. Inflammatory markers are associated with ventilator limitation and muscle dysfunction in lung disease in well-functioning elderly subjects // Thorax. – 2006; 61: P.10-16
11. Sharipova O.A., Bakhronov Sh.S., Rustamova G.R. Compative evaluation of the effectiveness of secondary stage prophylaxis in patients with chronic bronchitis witch delayed sexual dewelopment. East European Science Journal. Vienna, No. 11 (51). 2019. p. 61-64.