41 -1 (63) 2024 — Anvarxodjaeva Sh.G., Eshmurzaeva A.A. — PROGNOSTIC IMPLICATIONS OF AUTOIMMUNE THYROIDITIS IN THE CLINICAL COURSE OF RHEUMATOID ARTHRITIS

PROGNOSTIC IMPLICATIONS OF AUTOIMMUNE THYROIDITIS IN THE CLINICAL COURSE OF RHEUMATOID ARTHRITIS

Anvarxodjaeva Sh.G., Tashkent Medical Academy

Eshmurzaeva A.A. Tashkent Medical Academy

Resume

The literature review examines various aspects of the combination of rheumatoid arthritis (RA) with auto-immune thyroid diseases (Hashimoto’s thyroiditis and Graves’ disease). The prevalence, genetic predisposition, similarity of pathogenesis and clinical symptoms, as well as the ability of organ-specific autoantibodies (antibodies to thyroid peroxidase, antibodies to thyroglobulin) and hypothyroidism to influence the course of RA and the risk of cardiovascular complications are discussed.

Keywords: rheumatoid arthritis; autoimmune diseases of the thyroid gland; Hashimoto’s thyroiditis; Graves’ disease; antibodies to thyroid peroxidase; antibodies to thyroglobulin; hypothyroidism; cardio-vascular diseases.

First page

226

Last page

228

For citation: Anvarxodjaeva Sh.G., Eshmurzaeva A.A. – PROGNOSTIC IMPLICATIONS OF AUTOIMMUNE THYROIDITIS IN THE CLINICAL COURSE OF RHEUMATOID ARTHRITIS //New Day in Medicine 2024 1(63): 226-228 https://newdaymedicine.com/index.php/2024/01/19/l-769/

LIST OF REFERENCES:

1. Almutairi K, Nossent J, Preen D, Keen H, Inderjeeth C. The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review. // Rheumatol Int 2021; 41(5):863-77. doi: 10.1007/s00296-020-04731-0.
2. Collins J, Gough S. Autoimmunity in thyroid disease. // Eur J Nucl Med Mol Imaging 2002; 29 Suppl 2:417-24. doi: 10.1007/s00259-002-0848-8
3. Conigliaro P, D’Antonio A, Pinto S, Chimenti MS, Triggianese P, Rotondi M, et al. Autoimmune thyroid disorders and rheumatoid arthritis: A bidirectional interplay. // Autoimmun Rev 2020; 19(6):102-529. doi: 10.1016/ j.autrev.2020.102529
4. Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet 2017; 390(10101):1550-62. doi: 10.1016/S0140-6736(17)30703-1
5. Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Hypothyroidism.
6. Li Q, Laumonnier Y, Syrovets T, Simmet T. Yeast two-hybrid screening of proteins interacting with plasmin receptor subunit: C-terminal fragment of annexin A2. // Acta Pharmacol Sin 2011; 32(11):1411-8. doi: 10.1038/aps.2011.121
7. Mahagna H, Caplan A, Watad A, Bragazzi NL, Sharif K, Tiosano S, et al. Rheumatoid arthritis and thyroid dysfunction: A cross-sectional study and a review of the literature. // Best Pract Res Clin Rheumatol 2018; 32(5):683–91. doi: 10.1016/j.berh.2019.01.021
8. McCoy SS, Crowson CS, Gabriel SE, Matteson EL. Hypothyroidism as a risk factor for development of cardiovascular disease in patients with rheumatoid arthritis. // J Rheumatol 2012; 39(5):954-8. doi: 10.3899/jrheum.111076
9. Nazary K, Hussain N, Ojo RO, Anwar S, Kadurei F, Hafizyar F, et al. Prevalence of thyroid dysfunction in newly diagnosed rheumatoid arthritis patients. // Cureus. 2021; 13(9):e18204. doi: 10.7759/cureus.182043.
10. Ozcan M, Karakus MF, Gunduz OH, Tuncel U, Sahin H. Hearing loss and middle ear involvement in rheumatoid arthritis. // Rheumatol Int 2002; 22(1):16-9. doi: 10.1007/s00296-002-0185-z
11. Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. // Lancet 2010; 376(9746):1094-108. doi: 10.1016/S0140-6736(10)60826-4
12. Sapin R, Schlienger JL. [Thyroxine (T4) and tri-iodothyronine (T3) determinations: techniques and value in the assessment of thyroid function]. // Ann Biol Clin (Paris) 2003; 61(4):411-20.
13. Nat Rev Dis Primers 2022; 8(1):31. doi: 10.1038/s41572-022-00364-8
14. Torpy JM, Lynm C, Golub RM. JAMA patient page. Hyperthyroidism. // JAMA 2011; 306(3):330. doi: 10.1001/jama.306.3.330
15. Li Q, Wang B, Mu K, Zhang J, Yang Y, Yao W, et al. Increased risk of thyroid dysfunction among patients with rheumatoid arthritis. // Front Endocrinol 2019; 9:799. doi:10.3389/fendo.2018.00799