76 -2 (34) 2021 — Tailakova D.I., Vohidov U.G. — IMMUNOLOGY OF THE ORAL CAVITY IN CHILDREN WITH CONGENITAL CLEFT LIP AND PALATE LIVING IN ECOLOGICALLY UNFAVORABLE AREAS OF THE BUKHARA REGION

76 -2 (34) 2021 – Tailakova D.I., Vohidov U.G. – IMMUNOLOGY OF THE ORAL CAVITY IN CHILDREN WITH CONGENITAL CLEFT LIP AND PALATE LIVING IN ECOLOGICALLY UNFAVORABLE AREAS OF THE BUKHARA REGION

IMMUNOLOGY OF THE ORAL CAVITY IN CHILDREN WITH CONGENITAL CLEFT LIP AND PALATE LIVING IN ECOLOGICALLY UNFAVORABLE AREAS OF THE BUKHARA REGION

Tailakova D.I., Bukhara State Medical Institute.

Vohidov U.G. Bukhara State Medical Institute.

Resume

In connection with the continuing chemicalization of agriculture in the republic and the increasing intensification of industrial production, the danger of chemical pollution of objects of the human environment, disturbances in the ecological balance and their negative impact on the health of the population increases.

As you know, in the conditions of Uzbekistan, the main sources of environmental pollution in rural areas are the large-scale use of pesticides and mineral fertilizers, and in industrial cities – emissions from various industrial enterprises; in some cotton growing regions there is a combined pollution of the environment with pesticides, mineral fertilizers and industrial emissions.

Key words: pesticides: environmental pollution; children; congenital cleft lip and palate.

First page

392

Last page

397

For citation: Tailakova D.I., Vohidov U.G. Immunology of the oral cavity in children with congenital cleft lip and palate living in ecologically unfavorable areas of the Bukhara region //New Day in Medicine 2(34)2021 392-397 https://cutt.ly/HnXg4P4

List of References

1. Ешиев А.М., Дарбишев Э.П., Давыдова А.К. Частота и причины рождаемости детей с врожденными расщелинами по Южному региону Кыргызстана  // Молодой ученый. — 2014. — №21. — С. 39-41.
2. Долгих О.В., Зайцева Н.В., Дианова Д.Г. Анализ апоптотической активности лимфоцитов у женщин фертильного возраста в условиях воздействия репротоксикантов. // Российский иммунологический журнал.-2015.-Т.9 (18).- №1(1).-С. 58-59
3. Гаффоров С.А., Отабоев Ш.Т., Олимов С.Ш. Экологическая стабильность, стоматология и здоровье человека: пособие для педагогов высших учебных заведений, слушателей факультетов усовершенствования врачей, специалистов стоматологов и экологов, Ташкент «Академ нашр» – 2014, С. 119,127, 197-199
4. Чуйкин О.С., Топольницкий О.З. Этиология, патогенез, клиника, реабилитация детей с врожденной расщелиной верхней губы, неба в регионе с нефтехимической промышленностью // Научный журнал Успехи современного естествознания,-2015, №6, С. 70-76
5. Andersson EM, Feragen KB, Mikalsen D, Kaul J, Holla TM, Filip C. Bilateral Hypodontia in Adolescents With Pierre Robin Sequence//Cleft Palate Craniofac J. 2015; 52(4): 452-7.
6. Arnold KE et al. 2013 Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems. Biol. Lett. 9, 20130492.
7. Brydon CA, Conway J, Kling R, Mehta L, Jabs EW, Taub PJ. Cleft lip and/or palate: one organization’s experience with more than a quarter million surgeries during the past decade // Craniofac Surg. 2014; 25(5):1601-9.
8. Conway JC, Taub PJ, Kling R, Oberoi K, Doucette J, Jabs EW Ten-year experience of more than 35,000 orofacial clefts in Africa. // BMC Pediatr. 2015; 15:8.
9. Taylakova D.I, KamilovKh.P, Kasymov M.M. The prevalence of systemic hypoplasia in children depending on the adverse environmental conditions and their prevention / International journal for social studies. – 2019. – Vol 5 (4) – P. 25-33.
10. Taylakova D.I, KamilovKh.P. The influence of some environmental pollutants on the histogenesis of teeth in experimental rats  Europen journal of pharmaceutical and medical research.  – 2018. – Vol. 5 (11). – P.  255-258.
11.  Taylakova D.I, KamilovKh.P. Hypoplasia In Children Of The Bukhara Region And Measures For Their Prevention / 4th international eduindex multidisciplinary conference. – 2019. – P. 39-43.
12. Тайлакова Д.И., Тухтаев К.Р. Особенности эмбрионального и постнатального гистогенеза зубов в условиях загрязнения окружающей среды / Врач-аспирант. -2011.-  Москва,  № 6.2, С. 313-318.
13. Тайлакова Д.И. Определение эффективности метода анкетирования при выявлении характера влияния неблагоприятных экологических факторов на зубочелюстную систему у детей// Медицина и здравоохранение. – 2017. – С. 16-19.
14. Taylakova D.I., Kamilov Kh.P., Kasymov M.M. The prevalence of systemic hypoplasia in children depending on the adverse environmental conditions and their prevention// International journal for social studies. – 2019. – Vol 5. No 4 – Р. 25-33. [18].
15.  Taylakova D.I., Kamilov Kh.P. Evaluation of the influence of harmful substances on the formation of the teeth of the fetus and newborn rats// Science, research, development – 2019. – №17. 30.05-31.05. – Р. 123-127. [19].
16. Taylakova D.I., Kamilov Kh.P. The influence of some environmental pollutants on the histogenesis of teeth in experimental rats// Europen journal of pharmaceutical and medical research. – 2018. 5 (11). – Р. 255-258.
17. Khabibova N.N. Characteristic features of free-radical processes and antioxidant protection in the oral cavity during chronic recurrent aphthous stomatitis// European Science Review. – 2018. – P. 191-193.
18. Khabibova N.N. Changes in biochemical and immunological indicators mixed saliva of patients with chronic recurrent aphthous stomatitis// Еuropean journal of pharmaceutical and medical research. –2018. – (5) 11. – P. 143-145.
19. Khabibova N.N., Khadjimetov A.А. Some occurrence aspects of chronic recurrent aphthous stomatitis of the oral cavity// Global Journal of Medical, Physical and Health Education. – 2019. – Vol. 7 (3). – P. 284-286.
20. Khabibova N.N. Characteristic features of the biochemical indicators of mixed saliva in patients with chronic recurrent aphtosis stomatitis// Global Science Research Journals. – 2019. – Vol. 7 (8). – P. 521-526