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  • 82 -3 (27/2) 2019 — Ergashov O.I., Kenjayev Yo.M., — VACCINATION INDICATORS AND CLINICAL COURSE OF GASTROENTERITES IN CHILDREN VACCINATED AGAINST ROTAVIRUS INFECTION

82 -3 (27/2) 2019 — Ergashov O.I., Kenjayev Yo.M., — VACCINATION INDICATORS AND CLINICAL COURSE OF GASTROENTERITES IN CHILDREN VACCINATED AGAINST ROTAVIRUS INFECTION

VACCINATION INDICATORS AND CLINICAL COURSE OF GASTROENTERITES IN CHILDREN VACCINATED AGAINST ROTAVIRUS INFECTION

Ergashov O.I., Tashkent Medical Academia Temez branch.

Kenjayev Yo.M., Tashkent Medical Academia Temez branch.

Yakubova M., Tashkent Medical Academia Temez branch.

Mustanov J.F. Tashkent Medical Academia Temez branch.

Resume,

The рurрose of the study: To study the degree of vaccination and the clinical course of rotavirus gastroenteritis (RVGE) in children under 5 years of age.

Materials and methods: The study was conducted by the 4th children’s infectious clinical hosрital in Tashkent, in the рeriod from 2017 to 2018. The study involved 80 children vaccinated against rotavirus infection according to the national vaccination calendar, under 5 years of age, with an established diagnosis of acute diarrhea of rotavirusetiology. The feces of sick children were examined by enzyme immunoassay (ELISA) for the presence of rotavirus antigens. According to the degree of vaccination, patients are divided into main and control groups. The main group consisted of 53 children who received partial (Rota-1) and full (Rota-2) vaccination, the control group included 27 children who did not receive vaccination. Conclusion. The analysis of the level of vaccination showed that 44% of sick children received full vaccination, 22% of patients received a single vaccination and not vaccinated 34% of patients. The incidence rate among children age from 2 to 5 years showed an increase of 1.5 times. This indicator is directly dependent on sick children who have not received vaccination. In patients vaccinated, the clinical course of RVGE is characterized by a decrease in cases of hyperthermia and vomiting by 1.3 times, and the level of hyperthermia does not exceed subfebrile numbers. The number of diarrhea in all patients did not exceed 3-5 times, in 46% of patients did not exceed 3 days. There is a decrease in catarrhal phenomena 5 times, cases of severe course of 18%. After the vaccination against rotavirus infection was introduced into the national calendar, significant positive results were achieved in the clinical course of RVGE, which is a good indicator of the effectiveness of vaccination.

Keywords: rotavirus, vaccination, gastroenteritis

First page

303

Last page

306

For citation: Ergashov O.I., Kenjayev Yo.M. Yakubova M., Mustanov J.F. Vaccination indicators and clinical course of gastroenterites in children vaccinated against rotavirus infection//New Day in Medicine 3(27)2019 303-306 https://cutt.ly/QbxNwOF

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