28 -1(21) 2018 — Mirzaev K.K., Umurzakov S.K, — PHARMACOKINETICS OF ANTIBIOTICS IN EXPERIMENTAL GUNSHOT WOUNDS

PHARMACOKINETICS OF ANTIBIOTICS IN EXPERIMENTAL GUNSHOT WOUNDS

Mirzaev K.K., Andijan State Medical Institute

Umurzakov S.K, Andijan State Medical Institute

Azizov D.T. Andijan State Medical Institute

Resume,

Experimental studies on the pharmacokinetics of gentamicin were performed on 40 rabbits with various methods of injection after the infliction of gunshot wounds on extremities. The results showed that the method of lymphotropic antibiotic therapy provides a more stable and long-term saturation of blood. The highest and the longest retaining concentration of gentamicin in the lymph nodes and soft tissue of gunshot wounds is reached at lymphotropic method of injection.

Keywords: gunshot wound, lymphatic antibiotic therapy, antibiotics pharmacokinetics.

First page

96

Last page

97

For citation: Mirzaev K.K., Umurzakov S.K, Azizov D.T. Pharmacokinetics of antibiotics in experimental gunshot wounds //New Day in Medicine 1(21)2018 96-97 https://cutt.ly/mneoUIx

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