21 -2 (34/1) 2021 — Navruzova Sh. I., Akhmedov A.T., — FEATURES OF COMORBIDITY WITH CONGENITAL HEART DEFECTS IN CHILDREN

FEATURES OF COMORBIDITY WITH CONGENITAL HEART DEFECTS IN CHILDREN

Navruzova Sh. I., Bukhara State Medical Institute

Akhmedov A.T., Bukhara State Medical Institute

Khikmatova Sh. U. Bukhara State Medical Institute

Resume

The state of sick children aged 1 month to 18 years with congenital heart defects (CHD) against the background of comorbidity was studied. Of those examined, 77.5% of children, along with the underlying disease (CHD), were diagnosed with concomitant diseases – acute respiratory diseases (ARI). The authors argue that frequent acute respiratory infections can lead to a decrease in immunity and the formation of foci of chronic infections, the exacerbation of which is one of the reasons for the late surgical correction of congenital heart disease, resulting in a high risk of postoperative complications, mortality and a decrease in the quality of life of patients. The natural course of CHD against the background of comorbidity contributes to a decrease in the effectiveness of conservative therapy for heart failure.

Aim of study: clinical characteristics of congenital heart defects with comorbidity.

Materials and methods: the study included 160 sick children with congenital heart defects (CHD) under the age of 18 years. The control group consisted of 30 healthy peers (14 boys and 16 girls). Distributing sick children with CHD by gender, the structure determines the predominance of the male contingent. There are slightly more boys -88 (55.0 ± 0.3%) than girls-72 (45.0 ± 0.3%).

Resume: features of the functioning of immunity in critical periods of life, impaired cardiac hemodynamics and chronic hypoxemia are the cause of frequent acute respiratory infections and the development of an immunodeficiency state. Comorbidity significantly worsens the condition of patients with CHD, reduces the effectiveness of conservative treatment of heart failure, and causes a delay in the necessary surgical correction.

Key words:  immunity, comorbidity, conservative therapy, congenital heart defects, foci of infection.

First page

119

Last page

123

For citation: Navruzova Sh. I., Akhmedov A.T., Khikmatova Sh. U. Features of comorbidity with congenital heart defects in children //New Day in Medicine 2(34/1)2021 119-123 https://cutt.ly/wbRHn9G

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