74 -2 (30/2) 2020 — Agzamova M.N., Ismoilov F.M., — FATAL CASES ANALYSIS OF PATIENTS WITH DESTRUCTIVE FORMS OF ACUTE PANCREATITIS

FATAL CASES ANALYSIS OF PATIENTS WITH DESTRUCTIVE FORMS OF ACUTE PANCREATITIS

Agzamova M.N. -Tashkent Pediatric Medical Institute. 223, Bagishamal street, Tashkent, 100140. http://tashpmi.uz.

Ismoilov F.M. -Tashkent Pediatric Medical Institute. 223, Bagishamal street, Tashkent, 100140. http://tashpmi.uz.

Usarov A.M. -Tashkent Pediatric Medical Institute. 223, Bagishamal street, Tashkent, 100140. http://tashpmi.uz.

Zuparov K.F. -Tashkent Pediatric Medical Institute. 223, Bagishamal street, Tashkent, 100140. http://tashpmi.uz.

Resume,

The work is based on a retrospective analysis of 60 case histories of deceased patients with various forms of pancreatic necrosis for the period from 2009 to 2019. The main causes of pancreatic necrosis leading to death were violations of a healthy lifestyle and alcohol abuse (38.3%) and pathology of the biliary system (38.3%). From 2009 to 2019 years, 134 cases of pancreatic necrosis were recorded (60 – 44.8% died during this period). Of the 60 patients who died, 56 (93.3%) underwent surgical intervention. On the first day after hospitalization, 34 (56.7%) patients were operated ontime, within 2-10 days – 12 (20%). In the first (pre-infectious) phase of the disease, 26 patients died. 34 patients died in the second (infectious) phase, the predominant part of fatal outcomes was observed in the first phase of the disease against the background of hemodynamic disturbances and multiple organ failure, in the late stages of pancreatic necrosis, due to increased endotoxemia and the development of abdominal sepsis.

Key words: pancreatic necrosis, pancreas, fatal case, enzymatic toxic shock, multiple organ insufficiency.

First page

285

Last page

287

For citation: Agzamova M.N., Ismoilov F.M., Usarov A.M., Zuparov K.F., Fatal cases analysis of patients with destructive forms of acute pancreatitis//New Day in Medicine 2(30)2020 285-287 https://cutt.ly/fvsu3B4

List of References

  1. Blagovestnov D.A., Khvatov V.B., Upyrev A.V. Comprehensive treatment of acute pancreatitis and its complications. Surgery. 2018; 5: 68-75
  2. Gostishchev V.K., Glushko V.A. Pancreatic necrosis and its complications, the basic principles of surgical tactics. Surgery. 2003; 3: 50-54
  3. Dellinger EP Infectious complications of pancreatitis. Clinical microbiology and antimicrobial chemotherapy. 2018; 1 (2): 34-39.
  4. Zainutdinov A.M., Malkov I.S., Kirshin A.P. Prevention and treatment of purulent complications in patients with destructive pancreatitis. Kazan medical journal. 2018, (6): 821-826
  5. Kostyuchenko A.L., Filin V.I. Emergency Pancreatology: A Handbook for Physicians, 2nd Edition, revised and updated. St. Petersburg: Dean, 2018; 480s
  6. Ostrovsky V.K., Mashchenko A.V. Assessment of severity and prognosis of purulent-destructive diseases of the abdominal organs. Surgery. 2017, 1: 33-37
  7. Savelyev V.S., Filimonov M.I., Gelfand B.R., Burnevich S.Z. Clinical and morphological characteristics of pancreatic necrosis in the light of surgical treatment. Annals of surgery. 2017; 3: 58-62.
  8. Saveliev V.S., Filimonov M.I., Gelfand B.R., Burnevich S.Z. Pancreatic necrosis and pancreatogenic sepsis. The state of the problem. Annals of surgery. 2015, 1: 12-19
  9. Wyncol D.L. The management of severe acute necrotizing pancreatitis; an evidence – based review of the literature. Intensive Care Med 2009; 25: 2: 146-156.
  10. Olimxojaev F.X., Askarov T.A., Axmedov M.S. Characteristics of Liver Small Vessels during Posnatal Ontogenesis; New day in medicine; 4(28)2019; 398-402.

file

download