142 –2 (30/3) 2020 — Tashpulatova F.K., Abdusalomova M.I., — FREQUENCY AND NATURE OF ADVERSE REACTIONS FROM ANTI — TUBERCULOSIS DRUGS IN CHILDREN WITH TUBERCULOSIS

FREQUENCY AND NATURE OF ADVERSE REACTIONS FROM ANTI – TUBERCULOSIS DRUGS IN CHILDREN WITH TUBERCULOSIS

Tashpulatova F.K., –Tashkent Pediatrics Medical Institute, 100125 Uzbekistan Tashkent, Bogishamol 223.

Abdusalomova M.I., –Tashkent Pediatrics Medical Institute, 100125 Uzbekistan Tashkent, Bogishamol 223.

Resume,

In order to study the frequency and nature of tuberculosis drug use in children with tuberculosis, 101 children with tuberculosis aged 1-17 years who are on inpatient treatment in the regional children’s phthisiological hospital of the Tashkent region were examined. In the dynamics of 42 (41, 5±4, 8%) sick children, adverse reactions to taking anti- tuberculosis drugs were noted. The most common adverse reactions were gastrointestinal tract lesions (28, 5±6, 9%) and liver lesions (23, 8±6, 5%). The most common adverse reactions were observed in children with intra-thoracic lymph node tuberculosis (78, 5±6, 3%). Clinical manifestations of adverse reactions were correlated with changes in biochemical parameters. Adverse reactions, mainly in 47, 6±7, 7% of sick children, were moderate. In 92, 8±3, 9% of children with tuberculosis, adverse reactions from anti- tuberculosis drugs were eliminated.

Keywords: tuberculosis, children with tuberculosis, anti- tuberculosis drugs, adverse reactions

First page

539

Last page

542

For citation: Tashpulatova F.K., Abdusalomova M.I., Frequency and nature of adverse reactions from anti – tuberculosis drugs in children with tuberculosis//New Day in Medicine 2(30)2020 539-542 https://cutt.ly/OvPr5r6

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