58 -3 (31/2) 2020 — Allaberganov D.Sh., Tazhimova N. I. — LYMPHONIC CHANGE IN NEONATAL SEPSIS

LYMPHONIC CHANGE IN NEONATAL SEPSIS

Allaberganov D.Sh. -Tashkent Medical Academy.

Tazhimova N. I. -Tashkent Medical Academy.

Resume

The aim of this work was to study the morphological and morphometric features of the lymph nodes of children who died in the neonatal period from sepsis.

The research material was the results of pediatric autopsy. Lymph nodes of different localization were studied by general morphological, histochemical and morphometric methods. As a result of a comprehensive study, it was found that with neonatal sepsis, intrauterine acquired and secondary immunodeficiencies are noted. It was revealed that with intrauterine acquired immunodeficiency, the main morphological and functional zones of the peripheral organs of immunogenesis are immature, hypoplastic due to underpopulation of lymphocytes. With secondary immunodeficiencies in the lymph nodes, changes occur depending on damage to the cellular or humoral immunity in the form of emptying the corresponding structural and functional zones, replacing them with reticular and connective tissue, as well as the lack of activation of lymphocytes and light reproduction centers.

Conclusions: with intrauterine sepsis, there was a lag in the formation of the main morphofunctional zones of the lymph nodes; with postnatal sepsis, against the background of secondary immunodeficiency, the devastation of the corresponding structural and functional zones of the lymph nodes was noted depending on damage to the cellular or humoral immunity.

Key words: newborn, neonatal period, neonatal sepsis, early, late, intrauterine infection, lymph nodes, morphology.

First page

248

Last page

251

For citation: Allaberganov D.Sh., Tazhimova N. I., Lymphonic change in neonatal sepsis//New Day in Medicine 3(31)2020 248-251 https://cutt.ly/bxOvvNz

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