16 -3 (35) 2021 — Mukhitdinova K.Ο., Aleinik V.A. — INFLUENCE OF INFECTIOUS FACTORS ON CHANGES IN IMMUNOLOGICAL INDICATORS IN WOMEN IN THE EARLY PERIOD OF PREVENTION OF PREGNANCY

INFLUENCE OF INFECTIOUS FACTORS ON CHANGES IN IMMUNOLOGICAL INDICATORS IN WOMEN IN THE EARLY PERIOD OF PREVENTION OF PREGNANCY

Mukhitdinova K.Ο., Andijan State Medical Institute, Andijan, Uzbekistan

Aleinik V.A., Andijan State Medical Institute, Andijan, Uzbekistan

Babich S.M., Andijan State Medical Institute, Andijan, Uzbekistan

Negmatshaeva Kh.N., Andijan State Medical Institute, Andijan, Uzbekistan

Ibragimova S.R., Andijan State Medical Institute, Andijan, Uzbekistan

 Shokirova S.M. Andijan State Medical Institute, Andijan, Uzbekistan

Resume

The study studied changes in immunological parameters and protease inhibitors in women who have a full-fledged pregnancy with infections of the genitourinary system and women who have miscarriages with an infection of the genitourinary system in the early stages of up to 12 weeks of pregnancy. It was concluded that the presence of infectious factors in the absence of a significant proinflammatory immune response in early pregnancy and a sufficient corrective reaction of protease inhibitors and TGF-β1 may contribute to a favorable course of early pregnancy and the development of a full-fledged pregnancy. However, in the presence of infectious factors and the presence of an excessive pro-inflammatory immune response in early pregnancy and an insufficient corrective reaction of protease inhibitors and TGF-β1, it can contribute to an unfavorable course of early pregnancy and the development of miscarriages.

Key words: interleukins, protease inhibitors, early pregnancy, miscarriage, infections of the genitourinary system, inflammatory process.

First page

84

Last page

88

For citation: Mukhitdinova K.Ο., Aleinik V.A., Babich S.M., Negmatshaeva Kh.N., Ibragimova S.R., Shokirova S.M. INFLUENCE OF INFECTIOUS FACTORS ON CHANGES IN IMMUNOLOGICAL INDICATORS IN WOMEN IN THE EARLY PERIOD OF PREVENTION OF PREGNANCY //New Day in Medicine 3(35)2021 84-88 https://cutt.ly/kQDTVGS

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