14 -3 (65) 2024 - Khamidova Nargiza Kosimovna - IMMUNOLOGICAL PARAMETERS IN CHILDREN WITH HYMENOLEPIDOSIS

IMMUNOLOGICAL PARAMETERS IN CHILDREN WITH HYMENOLEPIDOSIS

Khamidova Nargiza Kosimovna Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

In children affected by hymenolepiasis, there was a convincing imbalance in the state of the T-link of the immune system, humoral factors and cytokine parameters, it was proved that the increase in clinical signs of the disease in these patients is directly proportional to changes in the immune system. Based on the assessment of the immune and cytokine status of patients with hymenolepiasis, such parameters as CD3+-, CD4+-, CD8+-, CD16+- lymphocytes in the blood, IRI, IL-4 and IFN-γ in blood serum were recommended as alternative criteria for immunodiagnosis. The inclusion of the immunocorrective drug immunal in the traditional therapy of children diagnosed with hymenolepidosis led to an improvement in the course of the disease, a decrease in the clinical manifestations of the disease, the elimination of secondary immunodeficiency in the immune and cytokine status of the body, and the normalization of these indicators. The developed algorithm for the treatment of these children made it possible to optimize the recommended complex therapy and increase the effectiveness of treatment.

Keywords: hymenolepiasis, children, immunal, cytokine

First page

67

Last page

71

For citation: Khamidova Nargiza Kosimovna - IMMUNOLOGICAL PARAMETERS IN CHILDREN WITH HYMENOLEPIDOSIS//New Day in Medicine 3(65)2024 67-71 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Нарзуллаев Н.У., Ҳамидова Н.Қ., Мирзоева М.Р. Гименолепидозли болаларда аллергик ринитнинг кечишига турли хил терапия турларининг клиник-иммунологик таъсири // Инфекция иммунитет ва фармакология. Тошкент, 2021; 2: 391-399. (14.00.00, №15).
  2. Азимова Н.М. Клинико-иммунологические показатели гименолепидоза и лямблиоза у детей с интоксикацией ЦНС // Сборник тезисов 4-го съезда неврологов Узбекистана. - Ташкент, 2012;167.
  3. Khamidova N.K., Narzullayev N.U., Mirzoeva M.R. Clinical and immunological study of the effect of different types of therapy on the course of allergic rhinitis in children with hymenolepiasis // Annals of the Romanian Society for Cell Biology. 2021; 3(30):1900-1908. (Scopus).
  4. Хамидова Н.К. Клинико-неврологические и иммунологические показатели у детей с гельминтной инвазии // Тиббиётда янги кун. Бухоро, 2022; 2/40(22):314-318. (14.00.00, №22)
  5. Ҳамидова Н.Қ. Бухоро аҳолиси болалари ўртасидаги гименолепидоз касаллигининг клиник ва эпидемиологик аспектлари. // Биология ва тиббиёт муаммолари. Самарқанд, 2022; 5(139):224-228. (14.00.00, №19).
  6. Хамидова Н. К. Клинико-иммунологические показатели гименолепидоза с аллергическим ринитом у детей в зависимости от видатерапии // Central Asian Journal Of Medical and Natural Sciences. 2021; 331-333.
  7. Khamidova N. K. Clinical and immunological study of the effect of various types of therapy on the course of allergic rhinitis in children with hymenolepiasis // World Medicine Journal. 2021; 1(1): 387-391.
  8. Хамидова Н.К. Клинико-эпидемиологическая характеристика детей с гименолипедозом в Бухаре // Инфекция иммунитет и фармокология. Тошкент, 2022; 3: 256-262.
  9. Khamidova N.K. Analysis of clinical and epidemiological indicators of hymenolepidosis among the children's population of Вukhara // Middle european scientific bulletin. Аmerica, 2022; 227-231.
  10. Нарзуллаев Н.У., Мирзоева М.Р., Ҳамидова Н.Қ. Гименолепидоз билан зарарланган болаларда даволаш-профилактика чора-тадбирлари ва клиник - иммунологик мезонлар // Журнал медицина и инновации. Тошкент, 2022; 3(7): 351-363.

    file

    download