56 -3 (65) 2024 - Boltayev E.B., Khasanova D.A. - THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA DURING PELVIC SURGERY

THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA DURING PELVIC SURGERY

Boltayev E.B. Bukhara State Medical Institute named after Abu Ali ibn Sina

Khasanova D.A. Samarkand State Medical University

Resume

Currently, one of the urgent problems in anesthesiology is safe and adequate sedation in regional anesthesia. According to the basic principles of modern anesthesiology, safe and effective sedation should ensure the protection of the patient's psycho-emotional sphere, the absence of awakening, the absence of pain and fear, the absence of nausea and vomiting in the postoperative period; at the same time, it should not cause respiratory depression and influence on hemodynamics, and should not be accompanied by a delayed recovery of psychomotor function. After studying the current literature and analyzing our own observations, we came to the conclusion that under conditions of regional anesthesia, sedation with dexmedetomidine is preferable, rather than propofol. Sedation with Dexmedetomidine leads to a decrease in the incidence of cognitive impairment in the early postoperative period, a decrease in the intensity of pain, a beneficial effect on recovery and activation after surgery, and is also associated with a lower incidence of hypoxemia and hypotension during surgery.

Keywords: sedation, regional anesthesia, dexmedetomidine.

First page

297

Last page

301

For citation: Boltayev E.B., Khasanova D.A. - THE ROLE OF DEXMEDETOMIDINE IN REGIONAL ANESTHESIA DURING PELVIC SURGERY//New Day in Medicine 3(65)2024 297-301 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Bergese SD, Candiotti KA, Bokesch PM, Zura A, Wisemandle W, Bekker AY. A Phase IIIb, Randomized, Double-blind, Placebo-controlled, Multicenter Study Evaluating the Safety and E‡cacy of Dexmedetomidine for Sedation During Awake Fiberoptic Intubation. American Journal of Therapeutics [Internet]. Ovid Technologies (Wolters Kluwer Health); 2010 Nov; 17(6):586–95. Available from:https://doi.org/10.1097/mjt.0b013e3181d69072
  2. Boltayev E.B. Choice of respiratory therapy in severe patients with new coronavirus infection covid-19 // Achievements of science and education. Founders: Olympus. 2020; 8:70-74.
  3. Boltayev E.B.U., Sabirov J.M. Organization of oxygen therapy using a nasal mask and ventura mask in severe patients with Covid-19 corona virus infection. // Eme. Jou. Edu. Dis.Lif. Lea. [Internet], 2021Aug. 24 [cited 2021 Oct.17]; 2(08):6-10.
  4. Boltayev Elmurod Bekmurod ugli. (2023). Choice of respiratory therapy in severe patients with new coronavirus infection COVID-19. // Eurasian Research Bulletin, 2023; 20:18-22. Retrieved from https://geniusjournals.org/index.php/erb/article/view/4107
  5. Candiotti KA, Bergese SD, Bokesch PM, Feldman MA, Wisemandle W, Bekker AY. Monitored Anesthesia Care with Dexmedetomidine: A Prospective, Randomized, Double-Blind, Multicenter Trial. Anesthesia & Analgesia [Internet]. Ovid Technologies (Wolters Kluwer Health); 2010 Jan; 110(1):47–56. Available from: https://doi. org/10.1213/ane.0b013e3181ae0856
  6. Ebert TJ, Hall JE, Barney JA, Uhrich TD, Colinco MD. The E†ects of Increasing Plasma Concentrations of Dexmedetomidine in Humans. Anesthesiology [Internet]. Ovid Technologies (Wolters Kluwer Health); 2000 Aug; 93(2):382–94. Available from: https://doi.org/10.1097/00000542– 200008000–00016
  7. Karelov АE, Lebedinskiy KM, Buravtsov VI. Anesthetic, analgetic, hypnotic – are the de…nitions important?. // Anesteziologii I Reanimatologii, 2015; 12(5):3-11. [In Russian]
  8. Khayotovich, K.D., Bekmurodugli, B.E. (2022). Case in clinical practice: Modern intensive care in the treatment of post-resuscitation complications caused by cardiac arrhythmias. ACADEMICIA: An International Multidisciplinary Research Journal.
  9. Koyirov A.K. et al. Non-invasive lung ventilation in acute respiratory failure caused by new coronavirus infection Covid-19 // New Day in Medicine, 2021; 1(33):107-114.
  10. Krasenkova EA, Ovechkin AY, Pyregov AV. Inˆuence of anesthetic techniques on occurrence of postoperative cognitive dysfunction in elderly patients undergoing gynecologicalsurgery. Bulletin of Russian State Medical University [Internet]. Pirogov Russian National Research Medical University; 2016;(4):51–5. Available from: https://doi. org/10.24075/brsmu.2016–04–08
  11. Kulikov АS, Lubnin АYu. Dexmedetomidine: new opportunities in the anesthesiology. Anesteziologiya i Reanimatologiya. 2013;(1):37–41. [In Russian]
  12. Precedex (dexmedetomidine). Hospira, Inc., Lake Forest, IL 60045 USA. Available from: http://medlibrary.org/lib/rx/ meds/precedex/page/1–7/
  13. Qoyirov A. Q., Azimov A. A., Boltayev E. B. (2022). The Role of High-Flow Ventilation in the Treatment of Acute Respiratory Failure. // Eurasian Research Bulletin, 2022; 15:89-101.
  14. Shodmonovov J.B. (2023). Conduct respiratory therapy in patients with severe coronavirus infection. // Eurasian Research Bulletin, 2023; 20:12-17.
  15. Svetlov VA, Zaytsev AYu, Kozlov SP. Balanced anesthesia based on regional blockades: strategy and tactics [Sbalansirovannaya anesteziya na osnove regionarnykh blokad: strategiya i taktika]. Anesteziologiya i reanimatologiya. 2006; 4:4–33. [In Russian]
  16. Wu W, Chen Q, Zhang L, Chen W. Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy. Journal of International Medical Research [Internet]. SAGE Publications; 2014 Feb 10; 42(2):516–22. Available from: https://doi.org/10.1177/0300060513515437
  17. Yarashev A.R., Boltaev E.B., Shabaev Y.K. A retrospective analysis of complications of percutaneous dilated tracheostomy // New day in medicine, 2020; 4(32):301-304.
  18. Болтаев Э. Б. (2022, October). Ўткир нафас етишмовчилиги билан асоратланган янги коронавирус инфекцияси COVID-19да ноинвазив ўпка вентиляцияси. In problems of modern surgery, international scientific and practical conference with the participation of foreign scientists materials. Андижанский государственный медицинский институт.
  19. Boltayev E.B., Umurov B.F. (2023). Liver Functional Status in Severe Forms of Covid-19 Disease. // Eurasian Research Bulletin, 20, 163–173. Retrieved from https://www.geniusjournals.org/index.php/erb/article/view/4534
  20. Хайитов Д.Х., Болтаев Э.Б. (2022). Постреанимацион касаллик натижасида келиб чикадиган асоратларни бартараф этишда замонавий интенсив терапия. Клиник амалиетда учраган холат. // Academic research in modern science, 2022;1(9):172-178.

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