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  • 4 -4 (66) 2024 - Satvaldieva E.S., Tuychiev D.B. - PROSPECTS FOR POSTOPERATIVE ANESTHESIA IN PEDIATRIC CARDIOVASCULAR SURGERY

4 -4 (66) 2024 - Satvaldieva E.S., Tuychiev D.B. - PROSPECTS FOR POSTOPERATIVE ANESTHESIA IN PEDIATRIC CARDIOVASCULAR SURGERY

PROSPECTS FOR POSTOPERATIVE ANESTHESIA IN PEDIATRIC CARDIOVASCULAR SURGERY

Satvaldieva E.S. Tashkent Pediatric Medical Institute, Fergana regional children's multidisciplinary medical center Fergana sh. Uzbekistan

Tuychiev D.B. Tashkent Pediatric Medical Institute, Fergana regional children's multidisciplinary medical center Fergana sh. Uzbekistan

Sayramov I.Kh. Tashkent Pediatric Medical Institute, Fergana regional children's multidisciplinary medical center Fergana sh. Uzbekistan

Ashurov D.R. Tashkent Pediatric Medical Institute, Fergana regional children's multidisciplinary medical center Fergana sh. Uzbekistan

Resume

Currently, opioid analgesia is popularized as the "Gold Standard" in many countries, especially in MDX and our country. Recent studies worldwide have focused on the many side effects of narcotic anesthesia and the complications that aggravate the postoperative period. Therefore, studying the problems of postoperative anesthesia in children's cardiac surgery and applying new methods and innovations to the field are among the most important topics in today's medicine. The aim of the study is to optimize postoperative analgesia in children's cardiac surgery by using intravenous dexmedetomidine and paracetamol drugs. Research materials and methods: This presented scientific project was conducted in the children's cardiosurgery and intensive care departments of Fergana Region Children's Multidisciplinary Medical Center in a randomized, open, prospective manner during 2019-2023. 100 patients aged 1 to 4 years who were treated at the center with a diagnosis of congenital heart defects were included in the study. The first group is the main study group (n=50), patients received a loading dose of dexmedetomidine intravenous infusion 1.0 μg/kg/h for 10 minutes at a rate of 0.8 μg/kg/h using a syringe pump 30 minutes after surgery. during, against the background of paracetamol injection, 15 mg/kg, intravenously) 2 hours after the operation and every 8 hours during the day for the purpose of planned combinative analgesia. Group 2 patients or control group, (n=50), analgesia with morphine 0.3 mg/kg, intramuscular, primary dose 2 hours after surgery and every 12 hours as indicated. On the first day of the operation, the patients underwent continuous hemodynamic (A/B, YuQS, ExoKG) and respiratory (SatO2, blood gas analysis, electrolytes and KIX, ) monitoring. FLACC was used as a pain scale, and RASS-scale (Richmond agitation and sedation scale) was used to determine the level of sedation. Levels of blood glucose and cortisol were determined for pain biochemical marker testing. Conclusion: when combined multimodal analgesia with dexmedetomidine and paracetamol provides not only adequate sedation, effective postoperative analgesia, but also prevents psychomotor agitation and delirium, reduces excitability to extubation, allows early activation of the patient.

Keywords: children, cardiac surgery, dexmedetomidine, analgosedation

First page

20

Last page

28

For citation: Satvaldieva E.S., Tuychiev D.B., Sayramov I.Kh., Ashurov D.R. - PROSPECTS FOR POSTOPERATIVE ANESTHESIA IN PEDIATRIC CARDIOVASCULAR SURGERY//New Day in Medicine 4(66)2024 20-28 https://newdayworldmedicine.com/en/article/3758

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