37 -4 (66) 2024 - Abdukadirova M.A., Khikmatullaeva A.S. - ETIOLOGICAL STRUCTURE OF VIRAL CIRRHOSIS OF THE LIVER
ETIOLOGICAL STRUCTURE OF VIRAL CIRRHOSIS OF THE LIVER
Abdukadirova M.A. The Research Institute of Virology of the Republican specialized scientific practical medical center of epidemiology, microbiology, infectious and parasitic diseases, Uzbekistan
Khikmatullaeva A.S. The Research Institute of Virology of the Republican specialized scientific practical medical center of epidemiology, microbiology, infectious and parasitic diseases, Uzbekistan
Mirrakhimova N.M. The Research Institute of Virology of the Republican specialized scientific practical medical center of epidemiology, microbiology, infectious and parasitic diseases, Uzbekistan
Bakieva Sh.R. The Research Institute of Virology of the Republican specialized scientific practical medical center of epidemiology, microbiology, infectious and parasitic diseases, Uzbekistan
Khodjaeva М.E. The Research Institute of Virology of the Republican specialized scientific practical medical center of epidemiology, microbiology, infectious and parasitic diseases, Uzbekistan
Resume
Liver cirrhosis (LC) is a significant cause of disability and mortality in people with chronic liver disease worldwide. In 2019, cirrhosis was responsible for 2.4% of deaths worldwide. With improved treatment of hepatitis B and hepatitis C virus infections, the epidemiology and burden of liver cirrhosis is changing. In this article, we highlight global trends in the epidemiology of cirrhosis, discuss the contribution of various hepatotropic viruses in the development of the disease, and study the burden of cirrhosis. Viral hepatitis remains the leading cause of cirrhosis worldwide, the prevalence of HDV cirrhosis is steadily increasing and the number of deaths from liver cirrhosis will increase in the next decade.
Keywords:liver cirrhosis, HBV infection, HDV infection, HCV infection, etiology.Key words: liver cirrhosis, HBV infection, HDV infection, etiology
First page
210
Last page
214
For citation: Abdukadirova M.A., Khikmatullaeva A.S., Mirrakhimova N.M., Bakieva Sh.R., Khodjaeva М.E. - ETIOLOGICAL STRUCTURE OF VIRAL CIRRHOSIS OF THE LIVER//New Day in Medicine 4(66)2024 210-214 https://newdayworldmedicine.com/en/article/3758
List of References
- Alberts C. J. et al. Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels: a systematic review. // Lancet Gastroenterol. Hepatol., 2022; 7:724 –735.
- Ajmera V. et al. Liver stiffness on magnetic resonance elastography and the MEFIB index and liver-related outcomes in nonalcoholic fatty liver disease: a systematic review and meta-analysis of individual participants. // Gastroenterology, 2022; 163:1079–1089.e5.
- Asrani S.K., Devarbhavi H., Eaton J. Kamath P.S. Burden of liver diseases in the world. // J. Hepatol., 2019.–Vol.70.–P.151–171.
- GBD 2017 Cirrhosis Collaborators. The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. // Lancet Gastroenterol. Hepatol., 2020. –Vol.5. – P.245–266.
- Ginès P. et al. Liver cirrhosis. Lancet, 2021. – Vol.398. –P.1359–1376.
- Golabi P. et al. Burden of non-alcoholic fatty liver disease in Asia, the Middle East and North Africa: Data from Global Burden of Disease 2009-2019. // J. Hepatol., 2021. – Vol.75. –Vol.795–809.
- Huang D.Q. et al. Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer. // Cell Metab., 2022. – Vol.34. – P.969–977.e2.
- Huang D.Q., El-Serag, H.B. & Loomba, R. Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention. Nat. Rev. Gastroenterol. // Hepatol., 2021. – Vol.18, 223–238.
- Huang D.Q. et al. Hepatocellular carcinoma incidence in alcohol-associated cirrhosis: systematic review and meta-analysis. // Clin. Gastroenterol. Hepatol., 2022. https://doi.org/10.1016/j.cgh.2022.06.032.
- Kondili L.A. et al. Impact of the COVID-19 pandemic on hepatitis B and C elimination: an EASL survey. // JHEP Rep., 2022. – Vol.4, 100531.
- Le M.H. et al. Chronic hepatitis B prevalence among foreign-born and U.S.-born adults in the United States, 1999-2016. // Hepatology, 2020.–Vol.71.– P.431–443.
- Loomba R., Friedman S.L. Shulman G.I. Mechanisms and disease consequences of nonalcoholic fatty liver disease. // Cell, 2021.–Vol.184.– P.2537–2564.
- Moon A.M., Singal A.G. Tapper E.B. Contemporary epidemiology of chronic liver disease and cirrhosis. Clin. Gastroenterol. // Hepatol., 2020.–Vol.18.–P.2650–2666.
- Orman E. S. et al. Trends in characteristics, mortality, and other outcomes of patients with newly diagnosed cirrhosis. // JAMA Netw. Open., 2019. – Vol.2, e196412.
- Razavi-Shearer D. et al. The disease burden of hepatitis B and hepatitis C from 2015 to 2030: the long and winding road [abstract OS050]. // J. Hepatol., 2022. – Vol.77 (Suppl. 1), S43.
- Tan D.J.H. et al. Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic review and meta-analysis. // Lancet Oncol., 2022. – Vol.23. –Vol.521–530.
- Tan D.J.H. et al. Global burden of liver cancer in males and females: changing etiological basis and the growing contribution of NASH. // Hepatology, 2022. https://doi.org/10.1002/hep.32758.
- Tapper E.B., Ufere N.N., Huang D.Q. Loomba R. Review article: current and emerging therapies for the management of cirrhosis and its complications. Aliment. Pharmacol. Ther., 2022. – Vol.55. – P.1099–1115.
- Tapper E.B. Parikh, N.D. Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study. // BMJ 362, k2817 (2018).
- The Global Health Observatory. Global health estimates: Leading causes of death. WHO https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/ghe-leading-causes-of-death.
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