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  • 89 -4 (66) 2024 - Avezova S.Y. - INFLUENCE OF URINARY CALLIDINOGENASE (KALGEN 0.15 PNA) ON ICP IN PATIENTS WITH CEREBRAL INFARCTION

89 -4 (66) 2024 - Avezova S.Y. - INFLUENCE OF URINARY CALLIDINOGENASE (KALGEN 0.15 PNA) ON ICP IN PATIENTS WITH CEREBRAL INFARCTION

INFLUENCE OF URINARY CALLIDINOGENASE (KALGEN 0.15 PNA) ON ICP IN PATIENTS WITH CEREBRAL INFARCTION

Avezova S.Y. Urgench branch of the Tashkent Medical Academy Uzbekistan, Khorezm region

Resume

Objective: Evaluation of the effect of urinary kallidinogenase (Kalgen 0.15) on ICP in patients with cerebral infarction. Methods: The study included 46 patients with acute ischemic stroke (30 men and 16 women). We divided all patients into 2 groups: a control group, which included 23 patients, who received traditional therapy, and a study group, which included the remaining 23 who, in addition to the indicated therapy, received Kalgen 0.15 PNA. We measured ICP non-invasively in all patients over time using the Kompleksmed 1.3 device. Results: Kalgen had a positive effect on ICP in patients in the study group. Many patients experienced a significant restoration of blood pressure to normal levels without the use of antihypertensive drugs. Conclusions: Kalgen 0.15 PNA (urinary kallidinogenase) reduces ICP by dilating blood vessels and reducing vascular resistance during cerebral infarction. Kalgen in complex therapy improves neurological deficits and cognitive status in patients with ischemic stroke.

Keywords:ischemic stroke, intracranial pressure, urinary kallidinogenase, kinin-kallikrein system, blood pressure.

First page

513

Last page

517

For citation: Avezova S.Y. - INFLUENCE OF URINARY CALLIDINOGENASE (KALGEN 0.15 PNA) ON ICP IN PATIENTS WITH CEREBRAL INFARCTION//New Day in Medicine 4(66)2024 513-517 https://newdayworldmedicine.com/en/article/3758

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