122 -4 (66) 2024 - Usarov A.M., Askarov T.A. - IMMUNOLOGICAL CHANGES IN SURGICAL SEPSIS

IMMUNOLOGICAL CHANGES IN SURGICAL SEPSIS

Usarov A.M. Tashkent Pediatric Medical Institute

Askarov T.A. Tashkent Pediatric Medical Institute

Ashurmetov A. Tashkent Pediatric Medical Institute

Ismoilov F.M. Tashkent Pediatric Medical Institute

Resume

Relevance of the topic. Acute inflammatory diseases of the abdominal organs are one of the most difficult areas of modern surgery. The difficulty of diagnosis, due to a wide variety of forms of the course of diseases, a significant number of complications, a tendency to an increase in mortality rates determine the relevance of scientific research in this area (Panchenkov R.T., 1990; Skripnichenko D.F. 1986.). Purpose: The therapeutic effect of endolymphatic therapy of drugs is based on several mechanisms: the creation of high concentrations of drugs in the lymph nodes and in the focus of inflammation, to come into contact with lymphocytes of the lymph nodes, normalization of the microcirculation system in microvessels and interstitium, immunomodulatory effect through the lymph nodes. Material and methods. The study involved 36 patients with acute inflammatory pathology of the abdominal organs, who were treated in the surgical departments of clinics in the city of Tashkent. The therapeutic effect of endolymphatic therapy of drugs is based on several mechanisms: the creation of high concentrations of drugs in the lymph nodes and in the focus of inflammation, to come into contact with the lymphocytes of the lymph nodes; normalization of the microcirculation system in micro vessels and interstitial; immunomodulatory effect through of lymphocytes of lymph nodes.

Keywords: Lymphatic system, direct controlled endolymphatic therapy (DCET), peritonitis, surgical infections, endolymphatic antibiotic therapy (ELAT).

First page

686

Last page

691

For citation: Usarov A.M., Askarov T.A., Ashurmetov A., Ismoilov F.M. - IMMUNOLOGICAL CHANGES IN SURGICAL SEPSIS//New Day in Medicine 4(66)2024 686-691 https://newdayworldmedicine.com/en/article/3758

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