11 -5 (67) 2024 - S.I. Indiaminov, N.A. Boltaev - FORENSIC SIGNIFICANCE OF MORPHOLOGICAL CHANGES IN THE BRAIN STRUCTURES OF PERSONS WHO DIE IN DIFFERENT TERMS OF EXTROCEREBRAL COMBINED INJURIES

FORENSIC SIGNIFICANCE OF MORPHOLOGICAL CHANGES IN THE BRAIN STRUCTURES OF PERSONS WHO DIE IN DIFFERENT TERMS OF EXTROCEREBRAL COMBINED INJURIES

S.I. Indiaminov Republican Specialized Traumatology and Orthopedics Scientific and Practical Medical Center

N.A. Boltaev Navoi branch of the Republican Scientific Center for Emergency Medical Care of the Ministry of Health of the Republic of Uzbekistan

Resume

In the article, in order to identify the nature and dynamics of morphological changes in the structures of the brain of people who died from combined polytrauma, the brains from 313 corpses of people who died from combined and multiple polytrauma were studied using the methods of forensic histological studies using an algorithm for studying vascular-tissue reactions in which there were no injuries to the skull and brain, which we designated as “extrocerebral polytrauma.” When selecting cases of death from polytrauma, we were based on anatomical and clinical classifications of combined and multiple injuries. It has been established that thanatogenesis of traumatic disease caused by combined extracerebral trauma varies depending on the severity, duration and complications of extracerebral combined (multiple) polytraumas. If the blood supply to the vessels is preserved, during the period of acute reaction to injury, the degree of participation of nervous tissue and blood vessels in the thanatogenesis of the traumatic disease is approximately the same. In later stages of injury with the development of anemic blood vessels, pericellular edema can be observed to predominate over perivascular edema over time of the traumatic disease. In this regard, the average volume density (VD) of bloodless vessels increases significantly as the duration of the traumatic disease caused by extracerebral combined and multiple trauma increases. It is noted that the glial index in the brain increases up to 9-12 hours after injury from 11.23±0.03 to 11.48±0.03. After 9-12 hours to 6-8 days, GI values decrease from 11.45±0.03 to 6.40±0.02 (P≤0.05). These data indicate that in victims with extracerebral combined polytrauma, 9-12 hours and 6-8 days after injury, regardless of the treatment, there is a progressive decrease in the glial index in brain tissue.

Keywords: brain, forensic significance, combined injury, morphological changes

First page

61

Last page

68

For citation: S.I. Indiaminov, N.A. Boltaev - FORENSIC SIGNIFICANCE OF MORPHOLOGICAL CHANGES IN THE BRAIN STRUCTURES OF PERSONS WHO DIE IN DIFFERENT TERMS OF EXTROCEREBRAL COMBINED INJURIES//New Day in Medicine 5(67)2024 61-68 https://newdayworldmedicine.com/en/article/3758

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