14 -5 (67) 2024 - Nuriddinova N.F., Kurbonova Z.Ch. - LABORATORY DIAGNOSTICS OF HEMOSTASIS INDICATORS ON THE BACKGROUND OF ANTIVIRUS THERAPY IN HCV ETIOLOGY OF LIVER CIRRHOSIS
LABORATORY DIAGNOSTICS OF HEMOSTASIS INDICATORS ON THE BACKGROUND OF ANTIVIRUS THERAPY IN HCV ETIOLOGY OF LIVER CIRRHOSIS
Nuriddinova N.F. Tashkent Medical Academy
Kurbonova Z.Ch. Tashkent Medical Academy
Zaynutdinova D.L. Tashkent Medical Academy
Resume
According to WHO data, there are approximately 325 million people in the world. A person is infected with parenteral hepatitis viruses, 500 mln. more people than In 2015, 1.34 million deaths were observed due to viral hepatitis. The physiology of the hemostasis system is directly related to the activity of the liver, because hepatocytes produce many coagulation factors, anticoagulant proteins, components of the fibrinolysis system, and factors that stimulate thrombopoiesis. Complications such as bleeding from esophageal varices, hematomas, hemorrhagic purpura, bleeding from the nose and gums, and menorrhagia in patients with chronic diffuse liver diseases remain an urgent clinical problem. Purpose: to evaluate laboratory diagnostics of hemostasis indicators against the background of antiviral therapy in liver cirrhosis with HCV etiology. Data were collected from patients treated with cirrhosis of the liver of HCV etiology in the departments of hematology and hepatobiliary pathology of the 1st clinic of the Tashkent Medical Academy in 2020-2023.
Keywords: liver cirrhosis, hepatitis, fibrinogen, platelet, bleeding.
First page
78
Last page
84
For citation: Nuriddinova N.F., Kurbonova Z.Ch., Zaynutdinova D.L. - LABORATORY DIAGNOSTICS OF HEMOSTASIS INDICATORS ON THE BACKGROUND OF ANTIVIRUS THERAPY IN HCV ETIOLOGY OF LIVER CIRRHOSIS//New Day in Medicine 5(67)2024 78-84 https://newdayworldmedicine.com/en/article/3758
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