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  • 114 -5 (67) 2024 - Tukhsanova N.E. - COMPARATIVE CHARACTERISTICS OF LYMPHOID FORMATIONS OF THE SMALL INTESTINE IN NORMAL AND UNDER THE INFLUENCE OF COTORAN

114 -5 (67) 2024 - Tukhsanova N.E. - COMPARATIVE CHARACTERISTICS OF LYMPHOID FORMATIONS OF THE SMALL INTESTINE IN NORMAL AND UNDER THE INFLUENCE OF COTORAN

COMPARATIVE CHARACTERISTICS OF LYMPHOID FORMATIONS OF THE SMALL INTESTINE IN NORMAL AND UNDER THE INFLUENCE OF COTORAN

Tukhsanova N.E. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This article provides a comparative analysis of the cellular composition of the epithelial cover of villi, as well as lymph nodes of the mesenteric part of the small intestine of rats in normal and experimental conditions. The study of the degree of infiltration by lymphocytes of the epithelial cover of the villi of the mesenteric part of the small intestine showed an increase in the number of large and medium lymphocytes against the background of a decrease in small ones in the early stages of postnatal development. When exposed to cotoran in lymphoid structures, the number of large and medium-sized lymphocytes increases, the content of small lymphocytes decreases. At the age of 3 months, these indicators approach the norm due to the restoration of lymphocytic balance.

Key words: rat, cotoran, lymphocytes, epithelial cover.

First page

659

Last page

663

For citation:Tukhsanova N.E. - COMPARATIVE CHARACTERISTICS OF LYMPHOID FORMATIONS OF THE SMALL INTESTINE IN NORMAL AND UNDER THE INFLUENCE OF COTORAN//New Day in Medicine 5(67)2024 659-663 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Аминова Г.Г., Григоренко Д.Е., Русина А.К. Морфологические особенности лимфоидных структур тонкой кишки //Морфология. 2000;118(6):53–56.
  2. Гусейнов Т.С., Гусейнова С.Т., Мейланова Р.Д. Морфология микроциркуляторного русла при ожоговом шоке и коррекции инфузией перфторана //Бюллетень экспериментальной биологии и медицины. 2013;155(1):125-129.
  3. Корниенко Е.А. Механизмы воздействия антибиотиков на кишечник. //Фарматека: Актуальные обзоры. 2010;2:33-37.
  4. Крыжановский В.А. Лимфоидные образования области перехода тонкой кишки в толстую в постнатальном онтогенезе: /Автореф. дис. … канд. мед. наук. М. : 2000:21.
  5. Норматов Р.А., Марьяновская Ю.В. Лимфоидная ткань кишечника как основа иммунной системы пищеварительного тракта //Молодой ученый. 2017;20:201–203. – URL
  6. Сагатов Т.А, Каттаходжаева Д.У, Сагдуллаева М.К. Морфологическое состояние тканевых элементов тонкой кишки при острой затравке пестицидами //Тошкент тиббиёт академияси ахборотномаси. 2016;3:29-31.
  7. Сапин М.Р. Лимфатическая система и ее роль в иммунных процессах. //Морфология. 2012;141(3):139. Sapin MR. The lymphatic system and its role in immune processes Morphology. 2012;141(3):139. (In Russ.).
  8. Сидоров П.И., Шелыгин К.В., Кирпич И.А. Использование лабораторных животных в токсикологическом эксперименте. /Методические рекомендации. 2009; М. 12 с.
  9. Рахматова М.Х. Формирование иммунной системы слизистой оболочки тонкой кишки и адаптивных реакций в постнатальном онтогенезе: /Автореф. дис. … докт. мед. наук. Т.: 2019;170.
  10. Хаитов Р.М. и др. Иммунология: Учебник для вузов. /М.: ГЭОТАР–Медиа, 2011;311.
  11. Guanxiang Liang, Nilusha Malmuthuge, Hua Bao, Paul Stothard, Philip J. Griebel, and Le Luo Guan. Transcriptome analysis reveals regional and temporal differences in mucosal immune system development in the small intestine of neonatal calves. //BMC Genomics. 2016;17:602. doi: 10. 1186/s12864-016-2957-y
  12. Lisa Chedik, Dominique Mias-Lucquin, Arnaud Bruyere, and Olivier Fardel. In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans. Int J Environ Res Public Health. 2017 Jul; 14 (7): 708. doi: 10. 3390/ijerph14070708
  13. Lopes FM, Varela Junior AS, Corcini CD, et al. Effect of glyphosate on the sperm quality of zebrafish Danio rerio. Aquat Toxicol 2014; 155: 322–326. doi: 10. 1016/j. aquatox. 2014. 07. 006
  14. Manuela Buettner and Matthias Lochner. Development and Function of Secondary and Tertiary Lymphoid Organs in the Small Intestine and the Colon. Front Immunol. 2016; 7: 342. doi: 10. 3389/ fimmu. 2016. 00342
  15. Ouwehand A, Isolauri E, Salminen S. The role of intestinal microflora for development of the immune system in early childhood. Eur J Nutr. 2012;41(1):132-137
  16. Tukhsanova N.E. Quantitative Relationship of Lymphocytes in the Lymphoid Nodules of the Small Intestine of Rats in Normal and Under the Influence of Kotoran// American Journal of Medicine and Medical Sciences. - 2019.-№9(12) РР. 467-470
  17. Tukhsanova N. E., Khojiev D.Ya., Khasanova D.A. Reactive changes the cellular composition of the lymphoid structures of the intestine under the expose of cotoran // Fundamentalis scientiam/ Madrid Spain. №4 (5) 2017, P. 77.127.
  18. Tuksanova Nasiba Esanovna , Shaxnoza Muzaffarovna Kamalova. The Influence Of Harmful Environmental Factors On The Anatomical Parameters Of The Small Intestine Of Rats. Journal of Pharmaceutical Negative Results ¦ Volume 13 ¦ Special Issue 9 ¦ 2022, 3502-3506
  19. Nasiba Esanovna Tuhsanova, Kristina Sergeevna Opolovnikova, Khushnud Yokubovich Kamolov. Changes in the Lymphoid Structures of the Small Intestine under the Influence of Adverse Environmental Factors. Turkish Online Journal of Qualitative Inquiry (TOJQI) Volume 12, Issue 7, July 2021: 9487-9493.

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