121 -5 (67) 2024 - Shaxizirova I.D., Akilov Kh.A. - FEATURES OF VITAMINS AND MICROELEMENTS AMONG CHILDREN WITH POST-COVID SYNDROME

FEATURES OF VITAMINS AND MICROELEMENTS AMONG CHILDREN WITH POST-COVID SYNDROME

Shaxizirova I.D. - Center for the Development of Professional Qualifications of Medical Workers under the Ministry of Health of the Republic of Uzbekistan

Akilov Kh.A. - Center for the Development of Professional Qualifications of Medical Workers under the Ministry of Health of the Republic of Uzbekistan

Resume

The article is devoted to the study of the composition of vitamins (B6, C, D) and trace elements (calcium, phosphorus and iron) in children with post-Covid syndrome. The study is based on data from a prospective examination of 253 children with confirmed COVID-19 (by nasopharyngeal smear or IgM COVID-19 blood enzyme-linked immunosorbent assay (ELISA) PCR diagnosis) who complained of subsequent symptoms. Covid syndrome (PCS) 12 weeks after COVID-19. As a result, it has been proven that the development of post-Covid syndrome in children infected with COVID-19 is 65.6%. Typical variants of the post-Covid syndrome in children: asthenic (7.1%), respiratory (8.3%), cardiac (18.6%), recurrent diseases of the ENT organs (7.9%), functional gastrointestinal diseases (38.7%), mixed version (19.4%). Children with PCS have deficiencies in electrolytes such as phosphorus, calcium, and iron, as well as vitamins B6, C, and D, indicating a strained immune system.

Key words: post-Covid syndrome, diagnosis, micronutrients, vitamin levels, children

First page

694

Last page

700

For citation:Shaxizirova I.D., Akilov Kh.A. - FEATURES OF VITAMINS AND MICROELEMENTS AMONG CHILDREN WITH POST-COVID SYNDROME//New Day in Medicine 5(67)2024 694-700 https://newdayworldmedicine.com/en/article/3758

List of References

1. Вржесинская О.А., Левчук Л.В., Коденцова В.М., Кошелева О.В., Переверзева О.Г., Ларионова З.Г. и др. Обеспеченность витаминами группы В детей дошкольного возраста (г. Екатеринбург). //Вопросы детской диетологии, 2016;14(4):17-22. doi: 10.20953/1727-5784-2016-4-17-22.
2. Захарова И. Н., Мальцев С.В., Боровик Т.Э., Яцык Г.В., Малявская С.И., Вахлова И.В. и др. Результаты многоцентрового исследования «Родничок» по изучению недостаточности витамина D у детей раннего возраста в России. Педиатрия. //Журнал им. Сперанского, 2015; 94(1):62-67.
3. Лайкам К.Э. Государственная система наблюдения за состоянием питания населения. //Федеральная служба государственной статистики. – 2021. http://www.gks.ru
4. Орлова С.В., Никитина Е.А., Прокопенко Е.В., Водолазкая А.Н., Татаринов В.В., Пигарёва Ю.А. Роль витаминов и минералов в нутритивной поддержке иммунитета при COVID-19. //Медицинский алфавит. 2021; 21: 12-21.
5. Торшин И. Ю., Громова О.А., Лиманова О.А., Егорова Е.Ю., Сардарян И.С., Юдина Н.В. и др. Роль обеспеченности микронутриентами в поддержании здоровья детей и подростков: анализ крупномасштабной выборки пациентов посредством интеллектуального анализа данных. //Педиатрия, 2015; 94(6): 68-78. doi: http://dx.doi.org/10.24110/0031-403X-2015-94-6-68-78.
6. Ямбулатов А.М., Устинова О.Ю. Развитие гиповитаминозов у детей дошкольного возраста, подвергающихся комплексному воздействию химических факторов промышленного происхождения. //Вестник Пермского университета. Серия: Биология, 2017; 1: 118-126.
7. Alexander J., Tinkov A., Strand T.A., Alehagen U., Skalny A., Aaseth J. Early nutritional interventions with zinc, selenium and vitamin D for raising anti-viral resistance against progressive COVID-19. Nutrients. 2020; 12(8): 2358. https://dx.doi.org/10.3390/nu12082358.
8. Berger M.M., Herter-Aeberli I., Zimmermann M.B., Spieldenner J., Eggersdorfer M. Strengthening the immunity of the Swiss population with micronutrients: A narrative review and call for action. //Clin. Nutr. ESPEN. 2021; 43: 39-48. https://dx.doi.org/10.1016/j.clnesp.2021.03.012.
9. DiNicolantonio J.J., O’Keefe J.H. Magnesium and vitamin D deficiency as a potential cause of immune dysfunction, cytokine storm and disseminated intravascular coagulation in COVID-19 patients. //Mo Med. 2021; 118(1): 68-73.
10. Gombart A.F., Pierre A., Maggini S. A review of micronutrients and the immune system–working in harmony to reduce the risk of infection. //Nutrients. 2020; 12(1): 236. https://dx.doi.org/10.3390/nu12010236.
11. Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. //Nat Rev Immunol, 2018; 8(9): 685–698;
12. Shakoor H., Feehan J., Al Dhaher A.S., Ali H.I., Platat C., Ismail L.C. et al. Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? //Maturitas. 2021; 143: 1-9. https://dx.doi.org/10.1016/j.maturitas.2020.08.003.

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