• Home
  • NEW DAY MEDICINE
  • 5 (67) 2024
  • 140 -5 (67) 2024 - Khodjiev B.F., Satvaldieva E.A. - OPTIMIZATION OF INTRAOPERATIVE MYOCARDIAL PROTECTION DURING CARDIAC SURGERY IN YOUNG CHILDREN

140 -5 (67) 2024 - Khodjiev B.F., Satvaldieva E.A. - OPTIMIZATION OF INTRAOPERATIVE MYOCARDIAL PROTECTION DURING CARDIAC SURGERY IN YOUNG CHILDREN

OPTIMIZATION OF INTRAOPERATIVE MYOCARDIAL PROTECTION DURING CARDIAC SURGERY IN YOUNG CHILDREN

Khodjiev B.F. - Tashkent Pediatric Medical Institute, National Children's Medical Center

Satvaldieva E.A. - Tashkent Pediatric Medical Institute, National Children's Medical Center

Kuralov E.T. - Tashkent Pediatric Medical Institute, National Children's Medical Center

Abdukadirov A.A. - Tashkent Pediatric Medical Institute

Resume

This article provides a brief overview of the current problem of modern pediatric cardioanesthesiology - intraoperative cardioplegic protection of the myocardium during open heart surgery. The combination of hypothermia and potassium cardioplegic arrest has become the most common method of myocardial protection in the evolution of myocardioprotection. The review touched upon the classification and types of cardioplegic solutions, their advantages and disadvantages based on meta-analyses. The current state of the problem is highlighted.

Key words: myocardium, cardioprotection, pediatric cardiac surgery, early age, intraoperative protection, cardiopulmonary bypass.

First page

794

Last page

799

For citation:Khodjiev B.F., Satvaldieva E.A., Kuralov E.T., Abdukadirov A.A. - OPTIMIZATION OF INTRAOPERATIVE MYOCARDIAL PROTECTION DURING CARDIAC SURGERY IN YOUNG CHILDREN //New Day in Medicine 5(67)2024 794-799 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Melrose DG, Dreyer B, Bentall HH, Baker JBE. Elective cardiac arrest.Lancet 1955; 269:21-2. DOI: 10.1016/s0140-6736(55)93381-x
  2. Chambers DJ, Fallouh HB. Cardioplegia and cardiac surgery: pharmacological arrest and cardioprotection during global ischemia and reperfusion. Pharmacol Ther 2010;127:41– 52. DOI: 10.1016/j.pharmthera.2010.04.001
  3. Bretschneider HJ. Survival time and recuperative time of the heart in normothermia and hypothermia. Verh Dtsch Ges Krei- slaufforsch 1964;30:11–34. https://pubmed.ncbi.nlm.nih.gov/14271639/
  4. Swan H. Clinical hypothermia: a lady with a past and some promise for the future. Surgery 1973; 73:736–58. DOI: 10.1097/00000658-195313830-00009
  5. Hosenpud JD, Bennett LE, Keck BM, Boucek MM, Novick RJ. The registry of the international society for heart and lung transplantation: eighteenth official report—2001. J Heart Lung Transplant 2001;20:805–15. DOI: 10.1016/s1053-2498(00)00138-8
  6. Manrique AM, Kelly K, Litchenstein SE. The effects of cardiopulmonary bypass following pediatric cardiac surgery. In: Muñoz R, Morell VO, da Cruz EM, Vetterly CG, eds. Critical Care of Children with Heart Disease. Basic Medical and Surgical Concepts. London: Springer-Verlag, 2010;103–20. https://link.springer.com/book/10.1007/978-3-030-21870-6
  7. Goodwin GW, Ahmad F, Doenst T, Taegtmeyer H. Energy provision from glycogen, glucose, and fatty acids on adrenergic stimulation of isolated working rat hearts. Am J Physiol 1998;274:H1239–47.
  8. DOI: 10.1152/ajpheart.1998.274.4.H1239
  9. Lopaschuk GD, Spafford MA, Marsh DR. Glycolysis is pre- dominant source of myocardial ATP production immediately after birth. Am J Physiol 1991;261:H1698–705. DOI: 10.1152/ajpheart.1991.261.6.H1698
  10. Julia PL, Kofsky ER, Buckberg GD, Young HH, Bugyi HI. Studies of myocardial protection in the immature heart. I. Enhanced tolerance of immature versus adult myocardium to global ischemia with reference to metabolic differences. J Thorac Cardiovasc Surg 1990;100:879–87. https://pubmed.ncbi.nlm.nih.gov/2246910/
  11. Imura H, Caputo M, Parry A, Pawade A, Angelini GD, Sule- iman MS. Age-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery. Circulation 2001;103:1551–6. DOI: 10.1161/01.cir.103.11.1551
  12. Gombosova I, Boknik P, Kirchhefer U, et al. Postnatal changes in contractile time parameters, calcium regulatory proteins, and phosphates. Am J Physiol 1998;274:H2123–32. doi: 10.1155/2019/2675972
  13. Перхов В.И. Послеоперационная летальность в федеральных кардиохирургических клиниках: гамбургский счет / Менеджер здравоохранения. 2017. No9. С.6-15.
  14. https://cyberleninka.ru/article/n/posleoperatsionnaya-letalnost-v-federalnyh-kardiohirurgicheskih-klinikah-gamburgskiy-schet/viewer
  15. Teoh KH, Mickle DA, Weisel RD, et al. Effect of oxygen tension and cardiovascular operations on the myocardial antioxidant enzyme activities in patients with tetralogy of Fallot and aorta-coronary bypass. J Thorac Cardiovasc Surg 1992;104:159–64. https://pubmed.ncbi.nlm.nih.gov/1614202/
  16. del Nido PJ, Mickle DA, Wilson GJ, et al. Evidence of myocardial free radical injury during elective repair of tetralogy of Fallot. Circulation 1987;76:V174–9. https://europepmc.org/article/med/2959398
  17. Клышко Н.К. Щава С.П., Фургал А.А., Раповка В.Г., Шуматов В.Б., Силаев А.А., Зенина А.А., Филиппова Е.А., Гончарук Р.А., Сорокин В.А. Кардиоплегия и защита миокарда в кардиохирургии: современные тенденции // Кардиология и сердечно-сосудистая хирургия. 2020. Т. 13, No2. С. 108-113;
  18. DOI: 10.17116/kardio202013021108
  19. Баяндин Н.Л. Кристаллоидная гипотермическая и кровяная нормотермическая кардиоплегия // Журнал имени академика Б.В. Петровского «Клиническая и экспериментальная хирургия», 2020. Т. 8[1]. No1. С. 80-89;
  20. Хубулава Г.Г., Наумов А.Б., Марченко С.П., Терешенко О.Ю., Кулемин Е.С., Романовский Д.Ю., Бирюков А.В. Модифицированная методика комбинированной кристаллоидно-кровяной холодовой кардиоплегии с уменьшенным объемом заполнения системы доставки для хирургической коррекции врожденных пороков сердца у детей // Детские болезни сердца и сосудов. 2019. No16 [1]. С. 5-15. DOI: 10.24022/1810-0686-2019-16-1-5-15. DOI: https://doi.org/10.24022/1810-0686-2019-16-1-5-15

    file

    download